Patient characteristics
| Patient . | TA-TMA . | Day post-HSCT . | LDH (normal range), U/L . | Haptoglobin (normal range, 16-200), mg/dL . | sC5b-9 (normal range, 72-244), ng/mL . | Serum creatinine (current-to-baseline ratio) . | Schistocytes . | Urine protein-to-creatinine ratio . | Quantity of antihypertensives . | Treated with eculizumab . |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Yes | +96 | 436 (135-395) | <7 | 301 | 0.5 | None | 7.2 | 4 | Yes, day +100 |
| 2 | Yes | +6 | 1293 (155-450) | 9 | 196 | 0.9 | 1+ | 3.2 | 2 | Yes, day +49 |
| 3 | Yes | +1 (auto 2 of 2) | 573 (135-395) | 114 | 243 | 2.3 | None | 7.9 | 1 | Yes, day +98 |
| 4 | Yes | +44 | 377 (100-325) | 23 | NA | 2.1 | None | 0.3 | 1 | No |
| 5 | Yes | +61 | 437 (135-395) | 112 | 369 | 0.8 | None | 5.3 | 4 | Yes, day +133 |
| 6 | Yes | +38 | 328 (87-246) | 22 | 338 | 1.9 | 1+ | 18.7 | 4 | Yes, day +128 |
| 7 | No | +28 | 218 (135-395) | <7 | 68 | 0.9 | None | 0.4 | 2 | No |
| 8 | No | +25 (auto 2 of 2) | NA | NA | NA | 0.9 | None | NA | 0 | No |
| 9 | No | +82 | NA | NA | NA | 1.2 | None | NA | 1 | No |
| 10 | No | +26 | 203 (155-450) | 149 | NA | 0.8 | None | 3.8 | 1 | No |
| 11 | No | +28 (auto 1 of 4) | 264 (100-325) | 145 | NA | 1.3 | None | 1.2 | 1 | No |
| Patient . | TA-TMA . | Day post-HSCT . | LDH (normal range), U/L . | Haptoglobin (normal range, 16-200), mg/dL . | sC5b-9 (normal range, 72-244), ng/mL . | Serum creatinine (current-to-baseline ratio) . | Schistocytes . | Urine protein-to-creatinine ratio . | Quantity of antihypertensives . | Treated with eculizumab . |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Yes | +96 | 436 (135-395) | <7 | 301 | 0.5 | None | 7.2 | 4 | Yes, day +100 |
| 2 | Yes | +6 | 1293 (155-450) | 9 | 196 | 0.9 | 1+ | 3.2 | 2 | Yes, day +49 |
| 3 | Yes | +1 (auto 2 of 2) | 573 (135-395) | 114 | 243 | 2.3 | None | 7.9 | 1 | Yes, day +98 |
| 4 | Yes | +44 | 377 (100-325) | 23 | NA | 2.1 | None | 0.3 | 1 | No |
| 5 | Yes | +61 | 437 (135-395) | 112 | 369 | 0.8 | None | 5.3 | 4 | Yes, day +133 |
| 6 | Yes | +38 | 328 (87-246) | 22 | 338 | 1.9 | 1+ | 18.7 | 4 | Yes, day +128 |
| 7 | No | +28 | 218 (135-395) | <7 | 68 | 0.9 | None | 0.4 | 2 | No |
| 8 | No | +25 (auto 2 of 2) | NA | NA | NA | 0.9 | None | NA | 0 | No |
| 9 | No | +82 | NA | NA | NA | 1.2 | None | NA | 1 | No |
| 10 | No | +26 | 203 (155-450) | 149 | NA | 0.8 | None | 3.8 | 1 | No |
| 11 | No | +28 (auto 1 of 4) | 264 (100-325) | 145 | NA | 1.3 | None | 1.2 | 1 | No |
Laboratory values are from the day the tested patient sample was collected. Lactate dehydrogenase (LDH) normal range values vary by age.
Auto, autologous transplantation; NA, not applicable (laboratory value not obtained in patient at given time).