Table 1. Intrauterine survival of... | American Society of Hematology

Table 1.

Intrauterine survival of Meox2Cre-Thbd-null mice

Mating: male Meox2Cre-Thbd^+/– × female Thbd^loxP/loxP
Offspring genotype	Male	Female	Total
E 15-18	—	—
Thbd^loxP/lacZ Meox2Cre	—	—	14
Thbd^+/lacZ Meox2Cre	—	—	11
Thbd^loxP/lacZ	—	—	11
Thbd^+/lox	—	—	7
3 weeks
Thbd^loxP/lacZ Meox2Cre	13	8	21*
Thbd^+/lacZ Meox2Cre	28	31	59
Thbd^loxP/lacZ	33	34	67
Thbd^+/lox	33	28	61

Mating: male Meox2Cre-Thbd^+/– × female Thbd^loxP/loxP
Offspring genotype	Male	Female	Total
E 15-18	—	—
Thbd^loxP/lacZ Meox2Cre	—	—	14
Thbd^+/lacZ Meox2Cre	—	—	11
Thbd^loxP/lacZ	—	—	11
Thbd^+/lox	—	—	7
3 weeks
Thbd^loxP/lacZ Meox2Cre	13	8	21*
Thbd^+/lacZ Meox2Cre	28	31	59
Thbd^loxP/lacZ	33	34	67
Thbd^+/lox	33	28	61

Genotype frequencies at 15 to 18 days postcoitum and at 3 weeks postpartum, statistically tested against expected frequencies. Findings indicate selective loss of Meox2Cre-Thbd-null mice between the 2 time points.

–, allele deleted; +, wild-type allele; E, embryonic day; lox, loxP-flanked gene.

P < .05 (χ² analysis).

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