Intrauterine survival of Meox2Cre-Thbd-null mice
| Mating: male Meox2Cre-Thbd+/– × female ThbdloxP/loxP . | |||
|---|---|---|---|
| Offspring genotype . | Male . | Female . | Total . |
| E 15-18 | — | — | |
| ThbdloxP/lacZ Meox2Cre | — | — | 14 |
| Thbd+/lacZ Meox2Cre | — | — | 11 |
| ThbdloxP/lacZ | — | — | 11 |
| Thbd+/lox | — | — | 7 |
| 3 weeks | |||
| ThbdloxP/lacZ Meox2Cre | 13 | 8 | 21* |
| Thbd+/lacZ Meox2Cre | 28 | 31 | 59 |
| ThbdloxP/lacZ | 33 | 34 | 67 |
| Thbd+/lox | 33 | 28 | 61 |
| Mating: male Meox2Cre-Thbd+/– × female ThbdloxP/loxP . | |||
|---|---|---|---|
| Offspring genotype . | Male . | Female . | Total . |
| E 15-18 | — | — | |
| ThbdloxP/lacZ Meox2Cre | — | — | 14 |
| Thbd+/lacZ Meox2Cre | — | — | 11 |
| ThbdloxP/lacZ | — | — | 11 |
| Thbd+/lox | — | — | 7 |
| 3 weeks | |||
| ThbdloxP/lacZ Meox2Cre | 13 | 8 | 21* |
| Thbd+/lacZ Meox2Cre | 28 | 31 | 59 |
| ThbdloxP/lacZ | 33 | 34 | 67 |
| Thbd+/lox | 33 | 28 | 61 |
Genotype frequencies at 15 to 18 days postcoitum and at 3 weeks postpartum, statistically tested against expected frequencies. Findings indicate selective loss of Meox2Cre-Thbd-null mice between the 2 time points.
–, allele deleted; +, wild-type allele; E, embryonic day; lox, loxP-flanked gene.
P < .05 (χ2 analysis).