Table 3.

Univariate analysis of the ASXL1 rs4911231 and BIM rs686952 variants in nilotinib-treated patients

FactorNo. of patients12-mo MMR24-mo MR424-mo MR4.524-mo FFS
%P%P%P%P
ASXL1 rs4911231 genotype   .28  .048  .31  .537 
 Good risk 23 78  66  32  86  
 Poor risk 55 67  42  20  92  
BIM rs686952 genotype   .52  .77  .17  .877 
 Good risk 33 70  45  31  91  
 Poor risk 43 70  50  16  88  
FactorNo. of patients12-mo MMR24-mo MR424-mo MR4.524-mo FFS
%P%P%P%P
ASXL1 rs4911231 genotype   .28  .048  .31  .537 
 Good risk 23 78  66  32  86  
 Poor risk 55 67  42  20  92  
BIM rs686952 genotype   .52  .77  .17  .877 
 Good risk 33 70  45  31  91  
 Poor risk 43 70  50  16  88  

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