Summary of targeted hot spot mutation sequencing of marrow aspirate material preserved on a Wright-Giemsa–stained slide or as a formalin-fixed, paraffin-embedded (FFPE) block (performed at BioReference Laboratories, Elmwood Park, NJ)
| Gene . | Alteration . | Variant category . | Coverage . | Allele frequency . | Complementary DNA change . | Marrow aspirate material . |
|---|---|---|---|---|---|---|
| TP53 | p.Tyr234Cys | Disease associated | 5 867 | 37.84 | c.701A>G | Slide |
| RUNX1 | p.? | Disease associated | 1 299 | 41.65 | c.508+2T>C | Slide |
| TP53 | p.Tyr234Cys | Disease associated | 13 361 | 40.66 | c.701A>G | FFPE block |
| RUNX1 | p.? | Disease associated | 593 | 37.27 | c.508+2T>C | FFPE block |
| Gene . | Alteration . | Variant category . | Coverage . | Allele frequency . | Complementary DNA change . | Marrow aspirate material . |
|---|---|---|---|---|---|---|
| TP53 | p.Tyr234Cys | Disease associated | 5 867 | 37.84 | c.701A>G | Slide |
| RUNX1 | p.? | Disease associated | 1 299 | 41.65 | c.508+2T>C | Slide |
| TP53 | p.Tyr234Cys | Disease associated | 13 361 | 40.66 | c.701A>G | FFPE block |
| RUNX1 | p.? | Disease associated | 593 | 37.27 | c.508+2T>C | FFPE block |