Baseline characteristics of SCD patients with and without ONFH, California, 1991-2013
| . | All . | ONFH . | No ONFH . | . | |||
|---|---|---|---|---|---|---|---|
| Variables . | N . | % . | N . | % . | N . | % . | P . |
| All | 6237 | 100.0 | 1356 | 21.7 | 4881 | 78.3 | — |
| Sex | |||||||
| Male | 2948 | 47.3 | 643 | 47.4 | 2305 | 47.2 | .8988 |
| Female | 3283 | 52.6 | 713 | 52.6 | 2570 | 52.7 | .9625 |
| Unknown | 6 | 0.1 | — | — | 6 | 0.1 | .1965 |
| Race/ethnicity | |||||||
| Non-Hispanic white | 176 | 2.8 | 35 | 2.6 | 141 | 2.9 | .5451 |
| African American | 5615 | 90.0 | 1255 | 92.6 | 4360 | 89.3 | .0005 |
| Hispanic | 252 | 4.0 | 43 | 3.2 | 209 | 4.3 | .0661 |
| Asian/Pacific Islander | 34 | 0.5 | 2 | 0.1 | 32 | 0.7 | .0246 |
| Other/unknown | 160 | 2.6 | 21 | 1.5 | 139 | 2.8 | .0074 |
| Birth year | |||||||
| <1940 | 65 | 1.0 | 20 | 1.5 | 45 | 0.9 | .0761 |
| 1940-1949 | 250 | 4.0 | 89 | 6.6 | 161 | 3.3 | <.0001 |
| 1950-1959 | 664 | 10.6 | 166 | 12.2 | 498 | 10.2 | .0313 |
| 1960-1969 | 1040 | 16.7 | 264 | 19.5 | 776 | 15.9 | .0018 |
| 1970-1979 | 1151 | 18.5 | 312 | 23.0 | 839 | 17.2 | <.0001 |
| 1980-1989 | 1369 | 21.9 | 318 | 23.5 | 1051 | 21.5 | .1310 |
| 1990-1999 | 1084 | 17.4 | 163 | 12.0 | 921 | 18.9 | <.0001 |
| 2000-2009 | 557 | 8.9 | 23 | 1.7 | 534 | 10.9 | <.0001 |
| 2010-2013 | 57 | 0.9 | 1 | 0.1 | 56 | 1.1 | .0002 |
| SCD severity | |||||||
| Less severe | 3583 | 57.4 | 494 | 36.4 | 3089 | 63.3 | <.0001 |
| More severe | 2654 | 42.6 | 862 | 63.6 | 1792 | 36.7 | <.0001 |
| Acute chest syndrome* | |||||||
| Yes | 1773 | 28.4 | 596 | 44.0 | 1177 | 24.1 | <.0001 |
| No | 4464 | 71.6 | 760 | 56.0 | 3704 | 75.9 | <.0001 |
| . | All . | ONFH . | No ONFH . | . | |||
|---|---|---|---|---|---|---|---|
| Variables . | N . | % . | N . | % . | N . | % . | P . |
| All | 6237 | 100.0 | 1356 | 21.7 | 4881 | 78.3 | — |
| Sex | |||||||
| Male | 2948 | 47.3 | 643 | 47.4 | 2305 | 47.2 | .8988 |
| Female | 3283 | 52.6 | 713 | 52.6 | 2570 | 52.7 | .9625 |
| Unknown | 6 | 0.1 | — | — | 6 | 0.1 | .1965 |
| Race/ethnicity | |||||||
| Non-Hispanic white | 176 | 2.8 | 35 | 2.6 | 141 | 2.9 | .5451 |
| African American | 5615 | 90.0 | 1255 | 92.6 | 4360 | 89.3 | .0005 |
| Hispanic | 252 | 4.0 | 43 | 3.2 | 209 | 4.3 | .0661 |
| Asian/Pacific Islander | 34 | 0.5 | 2 | 0.1 | 32 | 0.7 | .0246 |
| Other/unknown | 160 | 2.6 | 21 | 1.5 | 139 | 2.8 | .0074 |
| Birth year | |||||||
| <1940 | 65 | 1.0 | 20 | 1.5 | 45 | 0.9 | .0761 |
| 1940-1949 | 250 | 4.0 | 89 | 6.6 | 161 | 3.3 | <.0001 |
| 1950-1959 | 664 | 10.6 | 166 | 12.2 | 498 | 10.2 | .0313 |
| 1960-1969 | 1040 | 16.7 | 264 | 19.5 | 776 | 15.9 | .0018 |
| 1970-1979 | 1151 | 18.5 | 312 | 23.0 | 839 | 17.2 | <.0001 |
| 1980-1989 | 1369 | 21.9 | 318 | 23.5 | 1051 | 21.5 | .1310 |
| 1990-1999 | 1084 | 17.4 | 163 | 12.0 | 921 | 18.9 | <.0001 |
| 2000-2009 | 557 | 8.9 | 23 | 1.7 | 534 | 10.9 | <.0001 |
| 2010-2013 | 57 | 0.9 | 1 | 0.1 | 56 | 1.1 | .0002 |
| SCD severity | |||||||
| Less severe | 3583 | 57.4 | 494 | 36.4 | 3089 | 63.3 | <.0001 |
| More severe | 2654 | 42.6 | 862 | 63.6 | 1792 | 36.7 | <.0001 |
| Acute chest syndrome* | |||||||
| Yes | 1773 | 28.4 | 596 | 44.0 | 1177 | 24.1 | <.0001 |
| No | 4464 | 71.6 | 760 | 56.0 | 3704 | 75.9 | <.0001 |
Acute chest syndrome code began in October 2003.