Table 4.

Analysis of laboratory and clinical outcomes in combined data from the University of Ibadan, UIC, and Walk-PHaSST cohorts

NHigh riskNStandard riskP*
WBC count, × 103/µL 329 10.7 (8.5-13.5) 567 10.2 (8.2-12.6) .049 
Hemoglobin, g/dL 329 8.2 (7.2-9.3) 567 8.5 (7.5-9.5) .0055 
Reticulocyte, % 259 11.5 (7.9-16.7) 434 9.6 (6.2-13.9) 1.0 × 10−5 
VOCs ≥3/y, n (%) 329 181 (55) 567 306 (54) .3 
Stroke history, n (%) 329 57 (17) 567 53 (9) .0002 
NHigh riskNStandard riskP*
WBC count, × 103/µL 329 10.7 (8.5-13.5) 567 10.2 (8.2-12.6) .049 
Hemoglobin, g/dL 329 8.2 (7.2-9.3) 567 8.5 (7.5-9.5) .0055 
Reticulocyte, % 259 11.5 (7.9-16.7) 434 9.6 (6.2-13.9) 1.0 × 10−5 
VOCs ≥3/y, n (%) 329 181 (55) 567 306 (54) .3 
Stroke history, n (%) 329 57 (17) 567 53 (9) .0002 

Values are expressed as medians and IQRs.

*

P value adjusted for age, sex, hydroxyurea therapy, and site by using linear and logistic regression analysis.

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