Comparison of laboratory variables by genetic risk profile in patients with SCA from the UIC and Walk-PHaSST cohorts
. | N . | High risk . | N . | Standard risk . | P . |
---|---|---|---|---|---|
UIC | |||||
WBC count, × 103/µL | 94 | 10.4 (7.9-13.0) | 166 | 10.1 (8.0-12.1) | .3 |
Hemoglobin, g/dL | 94 | 8.5 (7.4-9.6) | 166 | 8.8 (8.0-9.6) | .6 |
Reticulocyte, % | 93 | 13.5 (9.1-16.9) | 166 | 11.8 (8.3-15.6) | .027 |
UK and US cohorts (Walk-PHaSST) | |||||
WBC count, × 103/µL | 157 | 10.1 (8.1-13.1) | 230 | 9.6 (7.5-12.2) | .069 |
Hemoglobin, g/dL | 157 | 8.4 (7.3-9.7) | 230 | 8.8 (7.9-9.8) | .025 |
Reticulocyte, % | 151 | 9.6 (7.4-15.8) | 212 | 8.2 (5.8-12.3) | .0003 |
. | N . | High risk . | N . | Standard risk . | P . |
---|---|---|---|---|---|
UIC | |||||
WBC count, × 103/µL | 94 | 10.4 (7.9-13.0) | 166 | 10.1 (8.0-12.1) | .3 |
Hemoglobin, g/dL | 94 | 8.5 (7.4-9.6) | 166 | 8.8 (8.0-9.6) | .6 |
Reticulocyte, % | 93 | 13.5 (9.1-16.9) | 166 | 11.8 (8.3-15.6) | .027 |
UK and US cohorts (Walk-PHaSST) | |||||
WBC count, × 103/µL | 157 | 10.1 (8.1-13.1) | 230 | 9.6 (7.5-12.2) | .069 |
Hemoglobin, g/dL | 157 | 8.4 (7.3-9.7) | 230 | 8.8 (7.9-9.8) | .025 |
Reticulocyte, % | 151 | 9.6 (7.4-15.8) | 212 | 8.2 (5.8-12.3) | .0003 |
Values are expressed as medians and IQRs.