Disease-related complications and comorbidities
| Complication or comorbidity . | No. . | % . |
|---|---|---|
| Hepatic | 20 | 87 |
| Iron overload | 18 | 78 |
| Cirrhosis | 2 | 9 |
| Recurrent acute chest syndrome and/or vaso-occlusive crisis | 19 | 83 |
| Neurologic* | 8 | 35 |
| Stroke | 6 | 26 |
| Moyamoya syndrome | 4 | 17 |
| Transient ischemic attack | 1 | 4 |
| Cardiac* | 7 | 30 |
| Systolic dysfunction | 5 | 22 |
| Diastolic dysfunction | 3 | 13 |
| Renal | 6 | 26 |
| End-stage renal disease on peritoneal dialysis | 3 | 13 |
| End-stage renal disease on hemodialysis | 1 | 4 |
| CRI with baseline creatinine 2.5-5.0 mg/dL | 2 | 9 |
| Pulmonary hypertension | 5 | 22 |
| Autoimmune | 2 | 9 |
| Multiple sclerosis | 1 | 4 |
| Rheumatoid arthritis | 1 | 4 |
| Complication or comorbidity . | No. . | % . |
|---|---|---|
| Hepatic | 20 | 87 |
| Iron overload | 18 | 78 |
| Cirrhosis | 2 | 9 |
| Recurrent acute chest syndrome and/or vaso-occlusive crisis | 19 | 83 |
| Neurologic* | 8 | 35 |
| Stroke | 6 | 26 |
| Moyamoya syndrome | 4 | 17 |
| Transient ischemic attack | 1 | 4 |
| Cardiac* | 7 | 30 |
| Systolic dysfunction | 5 | 22 |
| Diastolic dysfunction | 3 | 13 |
| Renal | 6 | 26 |
| End-stage renal disease on peritoneal dialysis | 3 | 13 |
| End-stage renal disease on hemodialysis | 1 | 4 |
| CRI with baseline creatinine 2.5-5.0 mg/dL | 2 | 9 |
| Pulmonary hypertension | 5 | 22 |
| Autoimmune | 2 | 9 |
| Multiple sclerosis | 1 | 4 |
| Rheumatoid arthritis | 1 | 4 |
The number of events do not add up to the total number of events because at least 1 patient in each group experienced more than 1 complication.