Table 1. Murphy staging system for... | American Society of Hematology

Table 1.

Murphy staging system for Burkitt lymphoma.

Notes:

1) Favorable disease for Magrath regimen is stage I or stage IIR AND normal LDH.

2) > 25% bone marrow involvement is defined as L3 ALL and is not included in this staging system.

Stage I:

Single nodal or extranodal site excluding mediastinum or abdomen

Stage II:

Single extranodal tumor with regional nodal involvement   Two extranodal tumors on one side of diaphragm   Primary gastrointestinal tumor with or without associated mesenteric nodes   Two or more nodal areas on one side of diaphragm

Stage IIR:

Completely resected intra-abdominal disease

Stage III:

Two single extranodal tumors on opposite sides of diaphragm   All primary intrathoracic tumors   All paraspinal or epidural tumors   All extensive primary intra-abdominal disease   Two or more nodal areas on opposite sides of diaphragm

Stage IIIA:

Localized, non-resectable abdominal disease

Stage IIIB:

Widespread multiorgan abdominal disease

Stage IV:

Initial CNS or bone marrow involvement (< 25%)

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