Frequency of cytogenetic of abnormalities in de novo and therapy-related myelodysplasia (MDS) and acute myeloid leukemia (AML).
| . | Cytogenetics . | ||
|---|---|---|---|
| Type of disease . | Unbalanced 5q−/−5, 7q−/−7, +8, % . | Balanced 11q23, 21q22 17q21, 16q22, % . | Normal karyotype, % . |
| de novo MDS | 15-25 | rare | 50-60 |
| t-MDS | 50-70 | rare | 5-10 |
| de novo AML | 15-25 | 15-20 | 40-50 |
| t-AML | 40-50 | 15-20 | 10-15 |
| . | Cytogenetics . | ||
|---|---|---|---|
| Type of disease . | Unbalanced 5q−/−5, 7q−/−7, +8, % . | Balanced 11q23, 21q22 17q21, 16q22, % . | Normal karyotype, % . |
| de novo MDS | 15-25 | rare | 50-60 |
| t-MDS | 50-70 | rare | 5-10 |
| de novo AML | 15-25 | 15-20 | 40-50 |
| t-AML | 40-50 | 15-20 | 10-15 |