Table 3. International Lymphoma... | American Society of Hematology

Table 3.

International Lymphoma Study*—secondary leukemia: SIR versus AER.

Abbreviations: SIR, standardized incidence ratio; AER, absolute excess risk; O, observed; E, expected; pt, patient; PY, person year

*Dores G et al.¹⁰

Observed leukemias = 169
Expected leukemias = 7.86
SIR ( = O/E) = 169/7.86 = 21.5
PY of follow-up: 255,778
\begin{eqnarray*}&&AER\ =\ \frac{O\ {-}\ E}{PY}\ =\ \frac{169\ {-}\ 7.86}{255,778}\ {\times}\ 10,000\\&&=\ 6.3\ excess\ cases\ per\ 10,000\ pt\ per\ y\end{eqnarray*}