Table 1.

Schedules of rituximab maintenance.

ReferencePatient populationMaintenance schedule
Abbreviations: SLL, small lymphocytic leukemia; EORTC, European Organization for Research on Treatment of Cancer. 
Hainsworth et al7  Untreated follicular and SLL Induction: Rituximab monotherapy (375 mg/m2 weekly × 4 weeks) 375 mg/m2 weekly × 4 weeks every 6 months × 3 times 
Ghielmini et al8  Untreated and relapsed follicular lymphoma Induction: Rituximab monotherapy (375 mg/m2 weekly × 4 weeks) 375 mg/m2 at month 2,4,6,8 after end of induction 
Gordan et al9  Patients with CD20+ lymphoproliferative disorders who had received at least 1 prior treatment 375 mg/m2 every time rituximab blood levels fall under 25 mg/mL (375 mg/m2 given every 3–4 months) 
Hagenbeek et al EORTC10  Relapsed follicular lymphoma 375 mg/m2 every 3 months × 2 years 
ReferencePatient populationMaintenance schedule
Abbreviations: SLL, small lymphocytic leukemia; EORTC, European Organization for Research on Treatment of Cancer. 
Hainsworth et al7  Untreated follicular and SLL Induction: Rituximab monotherapy (375 mg/m2 weekly × 4 weeks) 375 mg/m2 weekly × 4 weeks every 6 months × 3 times 
Ghielmini et al8  Untreated and relapsed follicular lymphoma Induction: Rituximab monotherapy (375 mg/m2 weekly × 4 weeks) 375 mg/m2 at month 2,4,6,8 after end of induction 
Gordan et al9  Patients with CD20+ lymphoproliferative disorders who had received at least 1 prior treatment 375 mg/m2 every time rituximab blood levels fall under 25 mg/mL (375 mg/m2 given every 3–4 months) 
Hagenbeek et al EORTC10  Relapsed follicular lymphoma 375 mg/m2 every 3 months × 2 years