Purpura fulminans (neonatalis or adult)

Superficial or deep vein thrombosis, pulmonary embolism

Thrombosis of “unusual” venous circulations (e.g., cerebral, hepatic, mesenteric, and renal veins; possibly arm, portal, and ovarian veins; not retinal vein or artery)

Warfarin-induced skin necrosis

Possibly arterial thrombosis (e.g., stroke, acute myocardial infarction)

Recurrent fetal loss

Possibly complications of pregnancy (e.g., intrauterine growth restriction, stillbirth, severe pre-eclampsia, abruptio placentae)