Hereditary (familial or primary) thrombophilia.
| Strongly Supportive Data |
| Antithrombin deficiency |
| Protein C deficiency |
| Protein S deficiency |
| Activated protein C resistance |
| Factor V Leiden |
| Prothrombin G20210A |
| Homocystinuria |
| Supportive Data |
| Increased plasma factors I (fibrinogen), II (prothrombin), VIII, IX, XI |
| Factor XIII polymorphisms |
| Hyperhomocysteinemia |
| Dysfibrinogenemia |
| Reduced tissue factor pathway inhibitor |
| Weakly Supportive Data |
| Reduced protein Z and Z-dependent protease inhibitor |
| Tissue plasminogen activator deficiency |
| Increased plasminogen activator inhibitor (PAI)-1 |
| Increased thrombin-activatable fibrinolysis inhibitor |
| Hypoplasminogenemia and dysplasminogenemia |
| Hypofibrinolysis |
| Strongly Supportive Data |
| Antithrombin deficiency |
| Protein C deficiency |
| Protein S deficiency |
| Activated protein C resistance |
| Factor V Leiden |
| Prothrombin G20210A |
| Homocystinuria |
| Supportive Data |
| Increased plasma factors I (fibrinogen), II (prothrombin), VIII, IX, XI |
| Factor XIII polymorphisms |
| Hyperhomocysteinemia |
| Dysfibrinogenemia |
| Reduced tissue factor pathway inhibitor |
| Weakly Supportive Data |
| Reduced protein Z and Z-dependent protease inhibitor |
| Tissue plasminogen activator deficiency |
| Increased plasminogen activator inhibitor (PAI)-1 |
| Increased thrombin-activatable fibrinolysis inhibitor |
| Hypoplasminogenemia and dysplasminogenemia |
| Hypofibrinolysis |