Refractoriness and alloimmunization rates after transfusing ABO-matched versus mismatched platelets.
| . | . | . | . | . | . | New antibodies . | ||
|---|---|---|---|---|---|---|---|---|
| Platelet transfusions . | Enrolled . | Female patients . | Possible prior sensitization* . | Platelet transfusions Median (range) . | Platelet refractoriness†P= .001 . | Anti-A/B‡ . | Anti-HLA . | Platelet-specific . |
| *Possible prior sensitization after pregnancy/transfusion. | ||||||||
| †1-hour post-transfusion corrected count increment less than 4500. | ||||||||
| ‡ ≥ three doubling dilution increase over their baseline. | ||||||||
| From Carr R et al. Br J Haematol. 1990;75:408–413.34 | ||||||||
| ABO Matched | 13 | 10 (77%) | 9 (69%) | 7 (5–19) | 1 (8%) | 0 | 1 (8%) | 1 (8%) |
| ABO Mismatched | 13 | 2 (15%) | 4 (31%) | 9 (4–30) | 9 (69%) | 7 (54%) | 5 (38%) | 4 (31%) |
| . | . | . | . | . | . | New antibodies . | ||
|---|---|---|---|---|---|---|---|---|
| Platelet transfusions . | Enrolled . | Female patients . | Possible prior sensitization* . | Platelet transfusions Median (range) . | Platelet refractoriness†P= .001 . | Anti-A/B‡ . | Anti-HLA . | Platelet-specific . |
| *Possible prior sensitization after pregnancy/transfusion. | ||||||||
| †1-hour post-transfusion corrected count increment less than 4500. | ||||||||
| ‡ ≥ three doubling dilution increase over their baseline. | ||||||||
| From Carr R et al. Br J Haematol. 1990;75:408–413.34 | ||||||||
| ABO Matched | 13 | 10 (77%) | 9 (69%) | 7 (5–19) | 1 (8%) | 0 | 1 (8%) | 1 (8%) |
| ABO Mismatched | 13 | 2 (15%) | 4 (31%) | 9 (4–30) | 9 (69%) | 7 (54%) | 5 (38%) | 4 (31%) |