Table 1.

Names and characteristics of commercial superparamagnetic iron oxide (SPIO) agents.

ClassificationAgentUS adopted nameTrade nameCoating materialHydrodynamic diameter
AMI-121, AMI-25, AMI-227, and Code 7228 are distributed by AMAG Pharmaceuticals/Guerbet; OMP and NC100150 are distributed by GE-Healthcare; SHU-555A and SHU-555C are distributed by Schering; VSOP-C184 is distributed by Ferropharm. 
Table is modified from Wang et al, 200140 and Corot et al, 2006.8  
Oral SPIO AMI-121 Ferumoxsil Lumirem, Gastromark Silicon 300 nm 
 OMP Ferristene Abdoscan Sulphonated styrene-divinylbenzene 3.5 μm 
SSPIO AMI-25 Ferumoxide Endorem, Feridex IV Dextran 80–180 nm 
 SHU-555A Ferucarbotran or Ferrixan Resovist, Cliavist Carboxydextran 60–62 nm 
USPIO VSOP-C184   Citrate 7 nm 
 NC100150 Feruglose Clariscan Pegylated Starch 20 nm 
 SHU-555C  Supravist Carboxydextran 21 nm 
 Code 7228 Ferumoxytol  Carboxymethyl Dextran 30 nm 
 AMI-227 Ferumoxtran-10 Sinerem, Combidex Dextran 15–40 nm 
ClassificationAgentUS adopted nameTrade nameCoating materialHydrodynamic diameter
AMI-121, AMI-25, AMI-227, and Code 7228 are distributed by AMAG Pharmaceuticals/Guerbet; OMP and NC100150 are distributed by GE-Healthcare; SHU-555A and SHU-555C are distributed by Schering; VSOP-C184 is distributed by Ferropharm. 
Table is modified from Wang et al, 200140 and Corot et al, 2006.8  
Oral SPIO AMI-121 Ferumoxsil Lumirem, Gastromark Silicon 300 nm 
 OMP Ferristene Abdoscan Sulphonated styrene-divinylbenzene 3.5 μm 
SSPIO AMI-25 Ferumoxide Endorem, Feridex IV Dextran 80–180 nm 
 SHU-555A Ferucarbotran or Ferrixan Resovist, Cliavist Carboxydextran 60–62 nm 
USPIO VSOP-C184   Citrate 7 nm 
 NC100150 Feruglose Clariscan Pegylated Starch 20 nm 
 SHU-555C  Supravist Carboxydextran 21 nm 
 Code 7228 Ferumoxytol  Carboxymethyl Dextran 30 nm 
 AMI-227 Ferumoxtran-10 Sinerem, Combidex Dextran 15–40 nm 
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