Table 1. Distinguishing between... | American Society of Hematology

Table 1.

Distinguishing between monoclonal B-cell lymphocytosis (MBL), chronic lymphocytic lymphoma (CLL), and small lymphocytic lymphoma (SLL).

	Clonal B-cells of CLL phenotype	Peripheral blood B-cell count <5 × 10⁹/L	Lymphadenopathy or hepatosplenomegaly
Reprinted with permission from Shanafelt T, Hanson CA. Monoclonal B-cell lymphocytosis: definitions and natural history. Leuk Lymphoma. 2009;50:493–497.⁴⁸
MBL	+	+	−
SLL	+	+	+
CLL	+	−	+/−

	Clonal B-cells of CLL phenotype	Peripheral blood B-cell count <5 × 10⁹/L	Lymphadenopathy or hepatosplenomegaly
Reprinted with permission from Shanafelt T, Hanson CA. Monoclonal B-cell lymphocytosis: definitions and natural history. Leuk Lymphoma. 2009;50:493–497.⁴⁸
MBL	+	+	−
SLL	+	+	+
CLL	+	−	+/−