Table 1.

WHO 2008: the mature B-cell neoplasms.

*These represent provisional entities or provisional subtypes of other neoplasms. 
Diseases shown in italics are newly included in the 2008 WHO classification. 
Chronic lymphocytic leukemia/small lymphocytic lymphoma 
B-cell prolymphocytic leukemia 
Splenic marginal zone lymphoma 
Hairy cell leukemia 
Splenic lymphoma/leukemia, unclassifiable 
    Splenic diffuse red pulp small B-cell lymphoma* 
    Hairy cell leukemia-variant* 
Lymphoplasmacytic lymphoma 
    Waldenström macroglobulinemia 
Heavy chain diseases 
    Alpha heavy chain disease 
    Gamma heavy chain disease 
    Mu heavy chain disease 
Plasma cell myeloma 
Solitary plasmacytoma of bone 
Extraosseous plasmacytoma 
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) 
Nodal marginal zone B-cell lymphoma (MZL) 
    Pediatric type nodal MZL 
Follicular lymphoma 
    Pediatric type follicular lymphoma 
Primary cutaneous follicle center lymphoma 
Mantle cell lymphoma 
Diffuse large B-cell lymphoma (DLBCL), not otherwise specified 
    T cell/histiocyte rich large B-cell lymphoma 
    DLBCL associated with chronic inflammation 
    Epstein-Barr virus (EBV)+DLBCL of the elderly 
Lymphomatoid granulomatosis 
Primary mediastinal (thymic) large B-cell lymphoma 
Intravascular large B-cell lymphoma 
Primary cutaneous DLBCL, leg type 
ALK+ large B-cell lymphoma 
Plasmablastic lymphoma 
Primary effusion lymphoma 
Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease 
Burkitt lymphoma 
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma 
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma 
Hodgkin Lymphoma 
Nodular lymphocyte-predominant Hodgkin lymphoma 
Classical Hodgkin lymphoma 
    Nodular sclerosis classical Hodgkin lymphoma 
    Lymphocyte-rich classical Hodgkin lymphoma 
    Mixed cellularity classical Hodgkin lymphoma 
    Lymphocyte-depleted classical Hodgkin lymphoma 
*These represent provisional entities or provisional subtypes of other neoplasms. 
Diseases shown in italics are newly included in the 2008 WHO classification. 
Chronic lymphocytic leukemia/small lymphocytic lymphoma 
B-cell prolymphocytic leukemia 
Splenic marginal zone lymphoma 
Hairy cell leukemia 
Splenic lymphoma/leukemia, unclassifiable 
    Splenic diffuse red pulp small B-cell lymphoma* 
    Hairy cell leukemia-variant* 
Lymphoplasmacytic lymphoma 
    Waldenström macroglobulinemia 
Heavy chain diseases 
    Alpha heavy chain disease 
    Gamma heavy chain disease 
    Mu heavy chain disease 
Plasma cell myeloma 
Solitary plasmacytoma of bone 
Extraosseous plasmacytoma 
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) 
Nodal marginal zone B-cell lymphoma (MZL) 
    Pediatric type nodal MZL 
Follicular lymphoma 
    Pediatric type follicular lymphoma 
Primary cutaneous follicle center lymphoma 
Mantle cell lymphoma 
Diffuse large B-cell lymphoma (DLBCL), not otherwise specified 
    T cell/histiocyte rich large B-cell lymphoma 
    DLBCL associated with chronic inflammation 
    Epstein-Barr virus (EBV)+DLBCL of the elderly 
Lymphomatoid granulomatosis 
Primary mediastinal (thymic) large B-cell lymphoma 
Intravascular large B-cell lymphoma 
Primary cutaneous DLBCL, leg type 
ALK+ large B-cell lymphoma 
Plasmablastic lymphoma 
Primary effusion lymphoma 
Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease 
Burkitt lymphoma 
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma 
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma 
Hodgkin Lymphoma 
Nodular lymphocyte-predominant Hodgkin lymphoma 
Classical Hodgkin lymphoma 
    Nodular sclerosis classical Hodgkin lymphoma 
    Lymphocyte-rich classical Hodgkin lymphoma 
    Mixed cellularity classical Hodgkin lymphoma 
    Lymphocyte-depleted classical Hodgkin lymphoma 
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