WHO 2008: the mature B-cell neoplasms.
*These represent provisional entities or provisional subtypes of other neoplasms. |
Diseases shown in italics are newly included in the 2008 WHO classification. |
Chronic lymphocytic leukemia/small lymphocytic lymphoma |
B-cell prolymphocytic leukemia |
Splenic marginal zone lymphoma |
Hairy cell leukemia |
Splenic lymphoma/leukemia, unclassifiable |
Splenic diffuse red pulp small B-cell lymphoma* |
Hairy cell leukemia-variant* |
Lymphoplasmacytic lymphoma |
Waldenström macroglobulinemia |
Heavy chain diseases |
Alpha heavy chain disease |
Gamma heavy chain disease |
Mu heavy chain disease |
Plasma cell myeloma |
Solitary plasmacytoma of bone |
Extraosseous plasmacytoma |
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) |
Nodal marginal zone B-cell lymphoma (MZL) |
Pediatric type nodal MZL |
Follicular lymphoma |
Pediatric type follicular lymphoma |
Primary cutaneous follicle center lymphoma |
Mantle cell lymphoma |
Diffuse large B-cell lymphoma (DLBCL), not otherwise specified |
T cell/histiocyte rich large B-cell lymphoma |
DLBCL associated with chronic inflammation |
Epstein-Barr virus (EBV)+DLBCL of the elderly |
Lymphomatoid granulomatosis |
Primary mediastinal (thymic) large B-cell lymphoma |
Intravascular large B-cell lymphoma |
Primary cutaneous DLBCL, leg type |
ALK+ large B-cell lymphoma |
Plasmablastic lymphoma |
Primary effusion lymphoma |
Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease |
Burkitt lymphoma |
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma |
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma |
Hodgkin Lymphoma |
Nodular lymphocyte-predominant Hodgkin lymphoma |
Classical Hodgkin lymphoma |
Nodular sclerosis classical Hodgkin lymphoma |
Lymphocyte-rich classical Hodgkin lymphoma |
Mixed cellularity classical Hodgkin lymphoma |
Lymphocyte-depleted classical Hodgkin lymphoma |
*These represent provisional entities or provisional subtypes of other neoplasms. |
Diseases shown in italics are newly included in the 2008 WHO classification. |
Chronic lymphocytic leukemia/small lymphocytic lymphoma |
B-cell prolymphocytic leukemia |
Splenic marginal zone lymphoma |
Hairy cell leukemia |
Splenic lymphoma/leukemia, unclassifiable |
Splenic diffuse red pulp small B-cell lymphoma* |
Hairy cell leukemia-variant* |
Lymphoplasmacytic lymphoma |
Waldenström macroglobulinemia |
Heavy chain diseases |
Alpha heavy chain disease |
Gamma heavy chain disease |
Mu heavy chain disease |
Plasma cell myeloma |
Solitary plasmacytoma of bone |
Extraosseous plasmacytoma |
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) |
Nodal marginal zone B-cell lymphoma (MZL) |
Pediatric type nodal MZL |
Follicular lymphoma |
Pediatric type follicular lymphoma |
Primary cutaneous follicle center lymphoma |
Mantle cell lymphoma |
Diffuse large B-cell lymphoma (DLBCL), not otherwise specified |
T cell/histiocyte rich large B-cell lymphoma |
DLBCL associated with chronic inflammation |
Epstein-Barr virus (EBV)+DLBCL of the elderly |
Lymphomatoid granulomatosis |
Primary mediastinal (thymic) large B-cell lymphoma |
Intravascular large B-cell lymphoma |
Primary cutaneous DLBCL, leg type |
ALK+ large B-cell lymphoma |
Plasmablastic lymphoma |
Primary effusion lymphoma |
Large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease |
Burkitt lymphoma |
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma |
B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma |
Hodgkin Lymphoma |
Nodular lymphocyte-predominant Hodgkin lymphoma |
Classical Hodgkin lymphoma |
Nodular sclerosis classical Hodgkin lymphoma |
Lymphocyte-rich classical Hodgkin lymphoma |
Mixed cellularity classical Hodgkin lymphoma |
Lymphocyte-depleted classical Hodgkin lymphoma |