Table 1.

Comparison of antibodies present in patients with sickle cell disease (SCD) receiving C-, E-, and K-matched donor units from minority donors (Group A) and patients with SCD receiving random donor units (Group B).

Group A (n = 20)Group B (n = 26)
*Often identified as apparent autoantibodies. 
Total number of antibodies 31 108 
    Common Rh alloantibodies 22 
  18 anti-E 
  4 anti-C 
    Complex Rh antibodies* 22 30 
 11 anti-D (D+ patients) 4 anti-D (D+ patients) 
 8 anti-e (e+ patients) 6 anti-e (e+ patients) 
 3 anti-C (C+ patients) 20 anti-C or -Ce (C+ patients) 
    Other antibodies 56 
 2 anti-Jkb 8 anti-K 1 anti-N 
 1 anti-Fya 6 anti-S 1 anti-Jsa 
 4 anti-M 6 anti-Fya 1 anti-Kpa 
 1 anti-N 4 anti-Jkb 1 anti-Yta 
 1 anti-Jsa 2 anti-Jka 1 anti-Lea 
  1 anti-M 1 anti-Leb 
  1 anti-Goa  
RHalleles 
    Hybrid RHD-CE-D and RHCE*ces 20 
    Only altered RHCE*ce 11 
    Partial RHD and altered RHCE*ce 14 
Group A (n = 20)Group B (n = 26)
*Often identified as apparent autoantibodies. 
Total number of antibodies 31 108 
    Common Rh alloantibodies 22 
  18 anti-E 
  4 anti-C 
    Complex Rh antibodies* 22 30 
 11 anti-D (D+ patients) 4 anti-D (D+ patients) 
 8 anti-e (e+ patients) 6 anti-e (e+ patients) 
 3 anti-C (C+ patients) 20 anti-C or -Ce (C+ patients) 
    Other antibodies 56 
 2 anti-Jkb 8 anti-K 1 anti-N 
 1 anti-Fya 6 anti-S 1 anti-Jsa 
 4 anti-M 6 anti-Fya 1 anti-Kpa 
 1 anti-N 4 anti-Jkb 1 anti-Yta 
 1 anti-Jsa 2 anti-Jka 1 anti-Lea 
  1 anti-M 1 anti-Leb 
  1 anti-Goa  
RHalleles 
    Hybrid RHD-CE-D and RHCE*ces 20 
    Only altered RHCE*ce 11 
    Partial RHD and altered RHCE*ce 14 

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