Comparison of antibodies present in patients with sickle cell disease (SCD) receiving C-, E-, and K-matched donor units from minority donors (Group A) and patients with SCD receiving random donor units (Group B).
. | Group A (n = 20) . | Group B (n = 26) . | |
---|---|---|---|
*Often identified as apparent autoantibodies. | |||
Total number of antibodies | 31 | 108 | |
Common Rh alloantibodies | 0 | 22 | |
18 anti-E | |||
4 anti-C | |||
Complex Rh antibodies* | 22 | 30 | |
11 anti-D (D+ patients) | 4 anti-D (D+ patients) | ||
8 anti-e (e+ patients) | 6 anti-e (e+ patients) | ||
3 anti-C (C+ patients) | 20 anti-C or -Ce (C+ patients) | ||
Other antibodies | 9 | 56 | |
2 anti-Jkb | 8 anti-K | 1 anti-N | |
1 anti-Fya | 6 anti-S | 1 anti-Jsa | |
4 anti-M | 6 anti-Fya | 1 anti-Kpa | |
1 anti-N | 4 anti-Jkb | 1 anti-Yta | |
1 anti-Jsa | 2 anti-Jka | 1 anti-Lea | |
1 anti-M | 1 anti-Leb | ||
1 anti-Goa | |||
RHalleles | |||
Hybrid RHD-CE-D and RHCE*ces | 3 | 20 | |
Only altered RHCE*ce | 11 | 6 | |
Partial RHD and altered RHCE*ce | 9 | 14 |
. | Group A (n = 20) . | Group B (n = 26) . | |
---|---|---|---|
*Often identified as apparent autoantibodies. | |||
Total number of antibodies | 31 | 108 | |
Common Rh alloantibodies | 0 | 22 | |
18 anti-E | |||
4 anti-C | |||
Complex Rh antibodies* | 22 | 30 | |
11 anti-D (D+ patients) | 4 anti-D (D+ patients) | ||
8 anti-e (e+ patients) | 6 anti-e (e+ patients) | ||
3 anti-C (C+ patients) | 20 anti-C or -Ce (C+ patients) | ||
Other antibodies | 9 | 56 | |
2 anti-Jkb | 8 anti-K | 1 anti-N | |
1 anti-Fya | 6 anti-S | 1 anti-Jsa | |
4 anti-M | 6 anti-Fya | 1 anti-Kpa | |
1 anti-N | 4 anti-Jkb | 1 anti-Yta | |
1 anti-Jsa | 2 anti-Jka | 1 anti-Lea | |
1 anti-M | 1 anti-Leb | ||
1 anti-Goa | |||
RHalleles | |||
Hybrid RHD-CE-D and RHCE*ces | 3 | 20 | |
Only altered RHCE*ce | 11 | 6 | |
Partial RHD and altered RHCE*ce | 9 | 14 |