Table 1. Revised classification criteria... | American Society of Hematology

Table 1.

Revised classification criteria for the antiphospholipid antibody syndrome.¹⁴

Clinical criteria (one or more)

Vascular thrombosis: One or more objectively confirmed episodes of arterial, venous or small vessel thrombosis occurring in any tissue or organ
Pregnancy morbidity:
- one or more unexplained deaths of a morphologically normal fetus at or beyond the 10^th week of gestation; or
- one or more premature births of a morphologically normal neonate before the 34^th week of gestation because of eclampsia, pre-eclampsia or placental insufficiency; or
- Three or more unexplained consecutive spontaneous abortions before the 10^th week of gestation

Laboratory criteria (one or more, present on 2 or more occasions at least 12 weeks apart using recommended procedures)

Lupus anticoagulant, detected according to the guidelines of the International Society on Thrombosis and Haemostasis
Anticardiolipin antibody of IgG and/or IgM isotype, present in medium or high titer (greater than 40 GPL or MPL, or greater than the 99^th percentile), measured by a standardized ELISA
Anti-β2-glycoprotein-1 antibody of IgG and/or IgM isotype, present in titer greater than the 99^th percentile, measured by a standardized ELISA