Table 1.

Risk of venous thromboembolism (VTE) conferred by type of thrombophilia.33 

ThrombophiliaOdds Ratios (95% CI)
Factor V Leiden – homozygosity 34.40 (9.86, 120.05)33  
Factor V Leiden – heterozygosity 8.32 (5.44, 12.70)33  
Prothrombin gene mutation – homozygosity 26.36 (1.24, 559.29)33  
Prothrombin gene mutation – heterozygosity 6.80 (2.46, 18.77)33  
Protein C deficiency 4.76 (2.15, 10.57)33  
Protein S deficiency 2.19 (1.48, 6.00)33  
Antithrombin deficiency 4.76 (2.15, 10.57) 
Methylene tetrahydrofolate reductase C677T – homozygosity 0.74 (0.22, 2.48)33  
Antiphospholipid antibodies 15.8 (10.9, 22.8)5  
ThrombophiliaOdds Ratios (95% CI)
Factor V Leiden – homozygosity 34.40 (9.86, 120.05)33  
Factor V Leiden – heterozygosity 8.32 (5.44, 12.70)33  
Prothrombin gene mutation – homozygosity 26.36 (1.24, 559.29)33  
Prothrombin gene mutation – heterozygosity 6.80 (2.46, 18.77)33  
Protein C deficiency 4.76 (2.15, 10.57)33  
Protein S deficiency 2.19 (1.48, 6.00)33  
Antithrombin deficiency 4.76 (2.15, 10.57) 
Methylene tetrahydrofolate reductase C677T – homozygosity 0.74 (0.22, 2.48)33  
Antiphospholipid antibodies 15.8 (10.9, 22.8)5  
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