Table 1. Select clinical trials in older... | American Society of Hematology

Table 1.

Select clinical trials in older adults with AML.

Study	Year	Median age, y	CR, %	Overall survival, mo
Induction death ~15%–25%
Disease-free survival ~6–9 months
ECOG 1490	1995³⁶	64	52	7.8
CALGB 8293	1995³⁷	69	52	9.6
SWOG 9031	1998³⁸	68	45	8.5
HOVON AML 9	1998¹⁷	68	42	9.5
MRC AML 11	2001¹²	66	55	10% – 5 yrs
CALGB 9720	2002³⁹	70	46	10
SWOG 9333	2002⁴⁰	68	43	9
ECOG 3993	2004¹⁵	68	42	7.5
AMLCG	2009⁴¹	66	59	16% – 4 yrs

Study	Year	Median age, y	CR, %	Overall survival, mo
Induction death ~15%–25%
Disease-free survival ~6–9 months
ECOG 1490	1995³⁶	64	52	7.8
CALGB 8293	1995³⁷	69	52	9.6
SWOG 9031	1998³⁸	68	45	8.5
HOVON AML 9	1998¹⁷	68	42	9.5
MRC AML 11	2001¹²	66	55	10% – 5 yrs
CALGB 9720	2002³⁹	70	46	10
SWOG 9333	2002⁴⁰	68	43	9
ECOG 3993	2004¹⁵	68	42	7.5
AMLCG	2009⁴¹	66	59	16% – 4 yrs