European LeukemiaNet (ELN) criteria for suboptimal response and failure at 3, 6, 12 and 18 months incorporating molecular responses at 6, 12 and 18 months based on analysis of the IRIS PCR data.
| . | Failure . | Suboptimal response . | Warning . |
|---|---|---|---|
| 3 months | No HR | No CHR, | |
| 6 months | No CHR | No MCR and/or >10% BCR-ABL (IS) | |
| 12 months | No MCR and/or >10% BCR-ABL (IS) | No CCR and/or >1% BCR-ABL (IS) | No MMR |
| 18 months | No CCR and/or >1% BCR-ABL (IS) | No MMR |
| . | Failure . | Suboptimal response . | Warning . |
|---|---|---|---|
| 3 months | No HR | No CHR, | |
| 6 months | No CHR | No MCR and/or >10% BCR-ABL (IS) | |
| 12 months | No MCR and/or >10% BCR-ABL (IS) | No CCR and/or >1% BCR-ABL (IS) | No MMR |
| 18 months | No CCR and/or >1% BCR-ABL (IS) | No MMR |