Revised European-American Lymphoma (REAL) and World Health Organization (WHO) classifications of T-cell and nNK neoplasms.
| REAL Classification . | WHO Classification . |
|---|---|
| Precursor T-cell neoplasm | Precursor T-cell neoplasm |
| Precursor T-lymphoblastic lymphoma/leukemia | Precursor T-lymphoblastic lymphoma/leukemia |
| Peripheral T-cell and NK-cell neoplasms | Mature (peripheral) T-cell neoplasms |
| T-cell chronic lymphocytic leukemia/Prolymphocytic leukemia | Predominantly leukemic/disseminated |
| T-cell prolymphocytic leukemia | |
| Large granular lymphocyte leukemia T-cell type and NK-cell type | T-cell granular lymphocytic leukemia |
| NK-cell leukemia | |
| Adult T-cell lymphoma/leukemia (HTLV1+) | Adult T-cell lymphoma/leukemia (HTLV1+) |
| Predominantly nodal | |
| Angioimmunoblastic T-cell lymphoma | Angioimmunoblastic T-cell lymphoma |
| Peripheral T-cell lymphoma, unspecified | Peripheral T-cell lymphoma, unspecified |
| Anaplastic large cell lymphoma, T/null-cell types | Anaplastic large-cell lymphoma, T/null-cell, primary systemic type |
| Predominantly extranodal | |
| Mycosis fungoides/Sézary syndrome | Mycosis fungoides/Sézary syndrome |
| Anaplastic large-cell lymphoma, T/null-cell, primary cutaneous type | |
| Angiocentric lymphoma | Extranodal NK/T-cell lymphoma, nasal type |
| Intestinal T-cell lymphoma (with or without enteropathy | Enteropathy-type T-cell lymphoma |
| Hepatosplenic γδ T-cell lymphoma | |
| Subcutaneous panniculitis-like T-cell lymphoma |
| REAL Classification . | WHO Classification . |
|---|---|
| Precursor T-cell neoplasm | Precursor T-cell neoplasm |
| Precursor T-lymphoblastic lymphoma/leukemia | Precursor T-lymphoblastic lymphoma/leukemia |
| Peripheral T-cell and NK-cell neoplasms | Mature (peripheral) T-cell neoplasms |
| T-cell chronic lymphocytic leukemia/Prolymphocytic leukemia | Predominantly leukemic/disseminated |
| T-cell prolymphocytic leukemia | |
| Large granular lymphocyte leukemia T-cell type and NK-cell type | T-cell granular lymphocytic leukemia |
| NK-cell leukemia | |
| Adult T-cell lymphoma/leukemia (HTLV1+) | Adult T-cell lymphoma/leukemia (HTLV1+) |
| Predominantly nodal | |
| Angioimmunoblastic T-cell lymphoma | Angioimmunoblastic T-cell lymphoma |
| Peripheral T-cell lymphoma, unspecified | Peripheral T-cell lymphoma, unspecified |
| Anaplastic large cell lymphoma, T/null-cell types | Anaplastic large-cell lymphoma, T/null-cell, primary systemic type |
| Predominantly extranodal | |
| Mycosis fungoides/Sézary syndrome | Mycosis fungoides/Sézary syndrome |
| Anaplastic large-cell lymphoma, T/null-cell, primary cutaneous type | |
| Angiocentric lymphoma | Extranodal NK/T-cell lymphoma, nasal type |
| Intestinal T-cell lymphoma (with or without enteropathy | Enteropathy-type T-cell lymphoma |
| Hepatosplenic γδ T-cell lymphoma | |
| Subcutaneous panniculitis-like T-cell lymphoma |