Selected results of immunosuppression with antithymocyte globulin (ATG) + cyclosporine (CsA) for aplastic anemia (AA).14,17 –19
| N . | Dx . | Ages (years) . | Response (%) . | Survival (%) . | Relapse (%) . | Study . |
|---|---|---|---|---|---|---|
| Abbreviations: Dx, diagnosis; SAA, severe AA; MAA, moderate AA; ALG, antilymphocyte globulin; CsA, cyclosporine; ATG, antithymocyte globulin; G-CSF, granulocyte colony-stimulating factor | ||||||
| 122 | SAA | <18 N = 31, >18 N = 91 | 61 at 6 mo 58 at 1 yr | 55 at 7 y | 35 at 5 y | NIH |
| 182 | SAA | Mean 25 | ALG+CsA 83 ATG+CsA+G-CSF 85 | NA | NA | EBMT/GITMO |
| 51 | SAA | Mean 43 | 70 at 6 mo | 64 at 3.5 y | 11 | Germany |
| 46 | MAA | Mean 29 | 74 at 6 mo | 93 at 4 y | NA | EBMT |
| 83 | SAA | 14–40 | 47 at 6 mo | 69 at 6 y | 7.1 | Korea |
| N . | Dx . | Ages (years) . | Response (%) . | Survival (%) . | Relapse (%) . | Study . |
|---|---|---|---|---|---|---|
| Abbreviations: Dx, diagnosis; SAA, severe AA; MAA, moderate AA; ALG, antilymphocyte globulin; CsA, cyclosporine; ATG, antithymocyte globulin; G-CSF, granulocyte colony-stimulating factor | ||||||
| 122 | SAA | <18 N = 31, >18 N = 91 | 61 at 6 mo 58 at 1 yr | 55 at 7 y | 35 at 5 y | NIH |
| 182 | SAA | Mean 25 | ALG+CsA 83 ATG+CsA+G-CSF 85 | NA | NA | EBMT/GITMO |
| 51 | SAA | Mean 43 | 70 at 6 mo | 64 at 3.5 y | 11 | Germany |
| 46 | MAA | Mean 29 | 74 at 6 mo | 93 at 4 y | NA | EBMT |
| 83 | SAA | 14–40 | 47 at 6 mo | 69 at 6 y | 7.1 | Korea |