Table 1.

Prognostic factors for outcome in histologic transformation.

Abbreviations: CR, complete response, HT, histologic transformation; CHOP, cyclophosphamide, hydroxydaunomycin, vincristine, prednisone; LDH, lactate dehydrogenase 
Prior CR for treatment of indolent lymphoma 
Absence of prior therapy 
CR following treatment for HT 
Normal LDH 
No marrow involvement 
Absence of B symptoms 
Stage (limited versus extensive) 
Treatment with a CHOP-like regimen 
Abbreviations: CR, complete response, HT, histologic transformation; CHOP, cyclophosphamide, hydroxydaunomycin, vincristine, prednisone; LDH, lactate dehydrogenase 
Prior CR for treatment of indolent lymphoma 
Absence of prior therapy 
CR following treatment for HT 
Normal LDH 
No marrow involvement 
Absence of B symptoms 
Stage (limited versus extensive) 
Treatment with a CHOP-like regimen 

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