Examples of individual immunophenotypic features with reported prognostic significance in diffuse large B-cell lymphomas (DLBCL).
| Immunophenotype . | Impact on Prognosis . |
|---|---|
| bcl-2 expression | adverse |
| bcl-6 expression | favorable |
| HLA class II expression | favorable |
| Mutated p53 | adverse |
| High proliferative rate defined by Ki-67 | adverse |
| Tumor-infiltrating lymphocytes | favorable |
| CD5 expression | adverse |
| MUM-1 positive | adverse |
| Cyclin D2 positive | adverse |
| Immunophenotype . | Impact on Prognosis . |
|---|---|
| bcl-2 expression | adverse |
| bcl-6 expression | favorable |
| HLA class II expression | favorable |
| Mutated p53 | adverse |
| High proliferative rate defined by Ki-67 | adverse |
| Tumor-infiltrating lymphocytes | favorable |
| CD5 expression | adverse |
| MUM-1 positive | adverse |
| Cyclin D2 positive | adverse |