Reduce the occurrence of venous thrombosis (VT) in a given family

Reduce the occurrence of VT in the general population

Help a family understand the disease their loved one is suffering

Improve the prescription of adequate VT prophylaxis in risk periods

Provide other health benefits such as:

Concurrent lipid and blood pressure screening

Opportunity for interventions for obesity and smoking

Limit ability to obtain health or life insurance

Cause undue psychological distress

Provide false reassurance to those testing negative (who probably do have a VT risk higher than the general population)