Comparison of relative risks of venous thrombosis in a retrospective (LETS) and prospective (LITE) study.
Risk Factor . | LETS . | LITE . |
---|---|---|
Abbreviations: LETS, Leiden Thrombophilia Study; LITE, Longitudinal Investigation of Thromboembolism Etiology; TAFI, thrombin-activatable fibrinolysis inhibitor | ||
Factor V Leiden | 8.1 | 3.7 |
Factor V Leiden homozygote | 80 | 24 |
Prothrombin 20210A | 2.8 | 1.9 |
Protein C deficiency | 3.1 | 3.4 |
Elevated factor V | 1.3 | 1.2 |
Antithrombin deficiency | 5.0 | Not done |
Elevated factor VIII | 4.8 | 2.6 |
Elevated factor VII | 0.8 | 2.4 |
Elevated factor IX | 2.8 | Not done |
Elevated factor XI | 2.2 | Not done |
Elevated fibrinogen | 4.0 | 0.9 |
Elevated TAFI | 1.7 | 1.6 |
Elevated D-dimer | 2.5 | 3.1 |
Elevated homocysteine | 2.5 | 1.5 |
Risk Factor . | LETS . | LITE . |
---|---|---|
Abbreviations: LETS, Leiden Thrombophilia Study; LITE, Longitudinal Investigation of Thromboembolism Etiology; TAFI, thrombin-activatable fibrinolysis inhibitor | ||
Factor V Leiden | 8.1 | 3.7 |
Factor V Leiden homozygote | 80 | 24 |
Prothrombin 20210A | 2.8 | 1.9 |
Protein C deficiency | 3.1 | 3.4 |
Elevated factor V | 1.3 | 1.2 |
Antithrombin deficiency | 5.0 | Not done |
Elevated factor VIII | 4.8 | 2.6 |
Elevated factor VII | 0.8 | 2.4 |
Elevated factor IX | 2.8 | Not done |
Elevated factor XI | 2.2 | Not done |
Elevated fibrinogen | 4.0 | 0.9 |
Elevated TAFI | 1.7 | 1.6 |
Elevated D-dimer | 2.5 | 3.1 |
Elevated homocysteine | 2.5 | 1.5 |