Table 1.

Comparison of relative risks of venous thrombosis in a retrospective (LETS) and prospective (LITE) study.

Risk FactorLETSLITE
Abbreviations: LETS, Leiden Thrombophilia Study; LITE, Longitudinal Investigation of Thromboembolism Etiology; TAFI, thrombin-activatable fibrinolysis inhibitor 
Factor V Leiden 8.1 3.7 
Factor V Leiden homozygote 80 24 
Prothrombin 20210A 2.8 1.9 
Protein C deficiency 3.1 3.4 
Elevated factor V 1.3 1.2 
Antithrombin deficiency 5.0 Not done 
Elevated factor VIII 4.8 2.6 
Elevated factor VII 0.8 2.4 
Elevated factor IX 2.8 Not done 
Elevated factor XI 2.2 Not done 
Elevated fibrinogen 4.0 0.9 
Elevated TAFI 1.7 1.6 
Elevated D-dimer 2.5 3.1 
Elevated homocysteine 2.5 1.5 
Risk FactorLETSLITE
Abbreviations: LETS, Leiden Thrombophilia Study; LITE, Longitudinal Investigation of Thromboembolism Etiology; TAFI, thrombin-activatable fibrinolysis inhibitor 
Factor V Leiden 8.1 3.7 
Factor V Leiden homozygote 80 24 
Prothrombin 20210A 2.8 1.9 
Protein C deficiency 3.1 3.4 
Elevated factor V 1.3 1.2 
Antithrombin deficiency 5.0 Not done 
Elevated factor VIII 4.8 2.6 
Elevated factor VII 0.8 2.4 
Elevated factor IX 2.8 Not done 
Elevated factor XI 2.2 Not done 
Elevated fibrinogen 4.0 0.9 
Elevated TAFI 1.7 1.6 
Elevated D-dimer 2.5 3.1 
Elevated homocysteine 2.5 1.5 

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