Table 3.

Strategies to improve the outcome of autologous stem cell transplantation (ASCT).

Improved induction regimens

  • -Integration of novel agents

 
Improved pre-ASCT conditioning regimens

  • -Escalation of melphalan dose

  • -Integration of novel agents

 
Tandem ASCT 
Improved post-ASCT measures

  • -Maintenance therapy

    • Alpha interferon

    • Corticosteroids

    • Thalidomide

    • Combination chemotherapy

    • Novel agents

  • Allogeneic SCT

 
Immunotherapy

  • -Vaccines

 
Improved induction regimens

  • -Integration of novel agents

 
Improved pre-ASCT conditioning regimens

  • -Escalation of melphalan dose

  • -Integration of novel agents

 
Tandem ASCT 
Improved post-ASCT measures

  • -Maintenance therapy

    • Alpha interferon

    • Corticosteroids

    • Thalidomide

    • Combination chemotherapy

    • Novel agents

  • Allogeneic SCT

 
Immunotherapy

  • -Vaccines

 
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