Comparison of adolescent/young adults with acute lymphoblastic leukemia (ALL) on pediatric versus adult clinical trials.27 –30
| Cooperative Group/Study Period . | No. of Patients . | CR (%),5-year . | EFS (%),5-year . |
|---|---|---|---|
| * 6-year EFS | |||
| † DFS | |||
| Abbreviations: CR, complete remission; EFS, event-free survival; DFS, disease-free survival | |||
| North America 1988–1998 Age of patients (yrs): 16–21 | |||
| CCG 1882 (peds) | 196 | 96 | 64* |
| CALGB 8811-9511 (adult) | 103 | 93 | 38* |
| French 1993–1994 Age of patients (yrs): 15–20 | |||
| FRALLE-93 (peds) | 77 | 94 | 67 |
| LALA-94 (adult) | 100 | 83 | 41 |
| Dutch 1985–1999 Age of patients (yrs): 15–20 | |||
| DCOG-ALL (peds) | |||
| 15–18 yrs | 47 | 98 | 69 |
| HOVON (adult) | |||
| 15–18 yrs | 44 | 91 | 34 |
| 19–20 yrs | 29 | 90 | 34 |
| Italian 1996–2000, Age of patients (yrs): 14–18 | |||
| AIEOP (peds) | 153 | 94 | 83† |
| GIMEMA (adults) | 95 | 95 | 55† |
| Cooperative Group/Study Period . | No. of Patients . | CR (%),5-year . | EFS (%),5-year . |
|---|---|---|---|
| * 6-year EFS | |||
| † DFS | |||
| Abbreviations: CR, complete remission; EFS, event-free survival; DFS, disease-free survival | |||
| North America 1988–1998 Age of patients (yrs): 16–21 | |||
| CCG 1882 (peds) | 196 | 96 | 64* |
| CALGB 8811-9511 (adult) | 103 | 93 | 38* |
| French 1993–1994 Age of patients (yrs): 15–20 | |||
| FRALLE-93 (peds) | 77 | 94 | 67 |
| LALA-94 (adult) | 100 | 83 | 41 |
| Dutch 1985–1999 Age of patients (yrs): 15–20 | |||
| DCOG-ALL (peds) | |||
| 15–18 yrs | 47 | 98 | 69 |
| HOVON (adult) | |||
| 15–18 yrs | 44 | 91 | 34 |
| 19–20 yrs | 29 | 90 | 34 |
| Italian 1996–2000, Age of patients (yrs): 14–18 | |||
| AIEOP (peds) | 153 | 94 | 83† |
| GIMEMA (adults) | 95 | 95 | 55† |