The association of age on immunophenotype and cytogenetics in acute lymphoblastic leukemia (ALL).
| . | Age (years) . | ||||
|---|---|---|---|---|---|
| Subgroup . | 1–9 . | 10–14 . | 15–19 . | 20–39 . | 40+ . |
| This data was extracted from the UKALL X and XA studies5 with the exception of the TEL-AML1 data, which was extracted from the ALL-AIEOP95 and ALL-BFM95 trials.25 | |||||
| B-cell | 86 | 68 | 70 | 60 | 75 |
| T-cell | 6 | 22 | 19 | 20 | 8 |
| Ploidy: | |||||
| Normal | 39 | 44 | 30 | 37 | 34 |
| Hypodiploid | 5 | 8 | 7 | 6 | 7 |
| Hyperdiploid | 37 | 20 | 29 | 16 | 15 |
| Tri-tetraploid | 2 | 3 | 4 | 1 | 8 |
| Chromosomes: | |||||
| TEL/AML1 t(12;21) | 24 | 18 | 5 | 0 | — |
| PBX1/E2A t(1;19) | 2 | 3 | 2 | 3 | 4 |
| MLL/AF4 t(4;11) | 1 | 2 | 2 | 0 | 9 |
| BCR/ABL t(9;22) | 1 | 3 | 4 | 12 | 19 |
| . | Age (years) . | ||||
|---|---|---|---|---|---|
| Subgroup . | 1–9 . | 10–14 . | 15–19 . | 20–39 . | 40+ . |
| This data was extracted from the UKALL X and XA studies5 with the exception of the TEL-AML1 data, which was extracted from the ALL-AIEOP95 and ALL-BFM95 trials.25 | |||||
| B-cell | 86 | 68 | 70 | 60 | 75 |
| T-cell | 6 | 22 | 19 | 20 | 8 |
| Ploidy: | |||||
| Normal | 39 | 44 | 30 | 37 | 34 |
| Hypodiploid | 5 | 8 | 7 | 6 | 7 |
| Hyperdiploid | 37 | 20 | 29 | 16 | 15 |
| Tri-tetraploid | 2 | 3 | 4 | 1 | 8 |
| Chromosomes: | |||||
| TEL/AML1 t(12;21) | 24 | 18 | 5 | 0 | — |
| PBX1/E2A t(1;19) | 2 | 3 | 2 | 3 | 4 |
| MLL/AF4 t(4;11) | 1 | 2 | 2 | 0 | 9 |
| BCR/ABL t(9;22) | 1 | 3 | 4 | 12 | 19 |