Clinical indications for transfusion.
| Methods . | Simple Transfusion . | Chronic Simple Transfusion . | Exchange Transfusion . |
|---|---|---|---|
| Conventional Indications | Symptomatic anemia Acute neurologic event Acute chest syndrome Acute multiorgan failure Preparation for major surgery Acute splenic or hepatic sequestration Sepsis and meningitis | Prevention of recurrent stroke Recurrent acute chest syndrome or multiorgan failure Symptomatic anemia with renal failure unresponsive to erythropoietin Pulmonary hypertension or chronic hypoxia Chronic heart failure | Acute neurologic event Severe acute chest syndrome Acute multiorgan failure Preparation for major surgery Chronic use, as for simple transfusion, to avoid/reduce iron loading |
| Controversial Indications | Before use of contrast media Severe ophthalmological complications | Recurrent debilitating pain events Non-healing leg ulcers Recurrent priapism | Acute priapism |
| Methods . | Simple Transfusion . | Chronic Simple Transfusion . | Exchange Transfusion . |
|---|---|---|---|
| Conventional Indications | Symptomatic anemia Acute neurologic event Acute chest syndrome Acute multiorgan failure Preparation for major surgery Acute splenic or hepatic sequestration Sepsis and meningitis | Prevention of recurrent stroke Recurrent acute chest syndrome or multiorgan failure Symptomatic anemia with renal failure unresponsive to erythropoietin Pulmonary hypertension or chronic hypoxia Chronic heart failure | Acute neurologic event Severe acute chest syndrome Acute multiorgan failure Preparation for major surgery Chronic use, as for simple transfusion, to avoid/reduce iron loading |
| Controversial Indications | Before use of contrast media Severe ophthalmological complications | Recurrent debilitating pain events Non-healing leg ulcers Recurrent priapism | Acute priapism |