Table 1

Main clinical characteristics of cHL patients, N = 49

CharacteristicNo.%
Median age, y (range) 32 (15-80)  
Sex, M/F 27/22 55/45 
Histology 
    Nodular sclerosis 37 76 
    Mixed cellularity 12 24 
EBV+* 16 36 
B symptoms 25 51 
Bulky mass 11 22 
Anemia, Hb level less than 105 g/L 12 24 
Leukocytosis, more than 15 × 109/L 18 
Lymphocytopenia, less than 0.6 × 109/L or less than 8% of WBC 14 
Hypoalbuminemia, less than 40 g/L 17 36 
High LDH level, more than 450 UI/L 18 37 
High β-2-microblobulin level, more than 25 mg/L 12 29 
Stage III-IV 23 47 
Hasenclever index more than 3 12 33 
CharacteristicNo.%
Median age, y (range) 32 (15-80)  
Sex, M/F 27/22 55/45 
Histology 
    Nodular sclerosis 37 76 
    Mixed cellularity 12 24 
EBV+* 16 36 
B symptoms 25 51 
Bulky mass 11 22 
Anemia, Hb level less than 105 g/L 12 24 
Leukocytosis, more than 15 × 109/L 18 
Lymphocytopenia, less than 0.6 × 109/L or less than 8% of WBC 14 
Hypoalbuminemia, less than 40 g/L 17 36 
High LDH level, more than 450 UI/L 18 37 
High β-2-microblobulin level, more than 25 mg/L 12 29 
Stage III-IV 23 47 
Hasenclever index more than 3 12 33 

WBC indicates white blood cell.

*

Nine (26%) of 34 nodular sclerosis versus 7 (70%) of 10 mixed cellularity (P = .01).

Calculated only in 36 patients with advanced disease (stages III-IV, B symptoms, or bulky mass).

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