Table 1 PML-RARα promoter occupancy Gene... | American Society of Hematology

Table 1

PML-RARα promoter occupancy

Gene ID	Symbol	Description	PML binding		PML binding primary patient leukemia cells—PCR	RARE position
Gene ID	Symbol	Description	U937chip	U937PCR	PML binding primary patient leukemia cells—PCR	RARE position
NM 013258	PYCARD	PYD and CARD domain–containing, transcript variant 1	1.63	16.45	ND	971-976 (−)
NM 000389	p21^CIP1/CDKN1A	Cyclin-dependent kinase inhibitor 1A	1.67	13.09	5.86	271-276 (−); 1194–1212 (−)
NM 006866	LILRA2	Homo sapiens leukocyte immunoglobulin-like receptor, subfamily A, member 2	3.13	12.19	ND	—
NM 181868	APAF1	Apoptotic protease–activating factor isoform d	1.36	7.52	3.05	—
NM 022047	DEF6	Differentially expressed in FDCP 6 homolog	4.32	7.01	3.82	107-112 (−)
NM 002159	HTN1	Histatin 1	2.83	6.59	3.97	798-803 (−)
NM 007067	MYST2	MYST histone acetyltransferase 2	1.51	6.28	2.60	—
NM 001005291	SREBF1	Sterol regulatory element binding transcription	1.50	4.41	5.58	380-385 (−)
NM 147166	AKAP9	A-kinase anchor protein 9 isoform 4	2.26	4.00	0.11	694-699 (−)
NM 001782	CD72	CD72 antigen	1.66	3.71	0.78	—
NM 005980	S100P	S100 calcium-binding protein P	1.57	3.51	6.41	697-702 (+)
NM 032883	C20orf100	Chromosome 20 open reading frame 100	1.46	3.48	1.31	—
NM 020349	ANKRD2	Homo sapiens ankyrin repeat domain 2	1.98	3.45	ND	—
NM 002923	RGS2	Homo sapiens regulator of G-protein signaling 2	1.34	3.32	ND	—
NM 000917	P4HA1	Proline 4-hydroxylase, alpha polypeptide I	1.40	2.53	6.11	—
NM 199077	CNNM2	Homo sapiens cyclin M2	1.84	2.49	ND	464-469 (−)
NM 000523	HOXD13	Homeobox D13	1.77	2.33	2.30	628-633 (−)
NM 177435	PPARD	Peroxisome proliferative activated receptor, delta	1.92	1.95	2.62	806-811 (+)
NM 003707	RUVBL1	RuvB-like 1 (E coli)	1.52	1.95	1.88	589-594 (+)
NM 020898	CALCOCO1	Homo sapiens calcium-binding and coiled-coil domain 1	1.68	1.54	1.21	—

Gene ID	Symbol	Description	PML binding		PML binding primary patient leukemia cells—PCR	RARE position
Gene ID	Symbol	Description	U937chip	U937PCR	PML binding primary patient leukemia cells—PCR	RARE position
NM 013258	PYCARD	PYD and CARD domain–containing, transcript variant 1	1.63	16.45	ND	971-976 (−)
NM 000389	p21^CIP1/CDKN1A	Cyclin-dependent kinase inhibitor 1A	1.67	13.09	5.86	271-276 (−); 1194–1212 (−)
NM 006866	LILRA2	Homo sapiens leukocyte immunoglobulin-like receptor, subfamily A, member 2	3.13	12.19	ND	—
NM 181868	APAF1	Apoptotic protease–activating factor isoform d	1.36	7.52	3.05	—
NM 022047	DEF6	Differentially expressed in FDCP 6 homolog	4.32	7.01	3.82	107-112 (−)
NM 002159	HTN1	Histatin 1	2.83	6.59	3.97	798-803 (−)
NM 007067	MYST2	MYST histone acetyltransferase 2	1.51	6.28	2.60	—
NM 001005291	SREBF1	Sterol regulatory element binding transcription	1.50	4.41	5.58	380-385 (−)
NM 147166	AKAP9	A-kinase anchor protein 9 isoform 4	2.26	4.00	0.11	694-699 (−)
NM 001782	CD72	CD72 antigen	1.66	3.71	0.78	—
NM 005980	S100P	S100 calcium-binding protein P	1.57	3.51	6.41	697-702 (+)
NM 032883	C20orf100	Chromosome 20 open reading frame 100	1.46	3.48	1.31	—
NM 020349	ANKRD2	Homo sapiens ankyrin repeat domain 2	1.98	3.45	ND	—
NM 002923	RGS2	Homo sapiens regulator of G-protein signaling 2	1.34	3.32	ND	—
NM 000917	P4HA1	Proline 4-hydroxylase, alpha polypeptide I	1.40	2.53	6.11	—
NM 199077	CNNM2	Homo sapiens cyclin M2	1.84	2.49	ND	464-469 (−)
NM 000523	HOXD13	Homeobox D13	1.77	2.33	2.30	628-633 (−)
NM 177435	PPARD	Peroxisome proliferative activated receptor, delta	1.92	1.95	2.62	806-811 (+)
NM 003707	RUVBL1	RuvB-like 1 (E coli)	1.52	1.95	1.88	589-594 (+)
NM 020898	CALCOCO1	Homo sapiens calcium-binding and coiled-coil domain 1	1.68	1.54	1.21	—

ND indicates not determined; and —, none.

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