Lineage analysis of normal versus leukemic populations
Population . | Naive ctrl, % . | GFP ctrl, % . | BCR, % . | BCR + Nup, % . | |||
---|---|---|---|---|---|---|---|
GFP+ . | GFP− . | GFP+ . | GFP− . | GFP+/YFP+ . | GFP−/YFP− . | ||
B cells | 30 | 47 | 21 | 37 | 16 | 15 | 13 |
T cells | 14 | 8 | 21 | 10 | 14 | 6 | 18 |
RBCs | 9 | 7 | 20 | 6 | 12 | 1 | 15 |
Myeloid | 36 | 28 | 31 | 34 | 46 | 46 | 43 |
Lin− | 11 | 10 | 6 | 12 | 12 | 32 | 11 |
Population . | Naive ctrl, % . | GFP ctrl, % . | BCR, % . | BCR + Nup, % . | |||
---|---|---|---|---|---|---|---|
GFP+ . | GFP− . | GFP+ . | GFP− . | GFP+/YFP+ . | GFP−/YFP− . | ||
B cells | 30 | 47 | 21 | 37 | 16 | 15 | 13 |
T cells | 14 | 8 | 21 | 10 | 14 | 6 | 18 |
RBCs | 9 | 7 | 20 | 6 | 12 | 1 | 15 |
Myeloid | 36 | 28 | 31 | 34 | 46 | 46 | 43 |
Lin− | 11 | 10 | 6 | 12 | 12 | 32 | 11 |
GFP ctrl indicates animals that received cells infected with the GFP control retrovirus; GFP+, percentage of indicated lineage within GFP+ (ie, infected) bone marrow cells; GFP−, percentage of indicated lineage within GFP− (ie, noninfected) bone marrow cells; BCR, animals that received cells infected with the BCR/ABL retrovirus; BCR + Nup, animals that received cells infected with the BCR/ABL and Nup98/HoxA9 retroviruses; and RBCs, red blood cells.