Biodistribution of AAV2-hF.IX vector genomes in rhesus monkeys 10 months after liver-directed gene transfer
| Tissue . | No IS . | MMF, sirolimus, daclizumab . | MMF, sirolimus . |
|---|---|---|---|
| Kidney | 0.0109 | 0.0967 | 0.0562 |
| Cortex | 0.0197 | 0.0217 | 0.0254 |
| Testis | 0.0213 | 0.0843 | 0.0623 |
| Psoas | 0.0022 | 0.0014 | 0.0000 |
| Thymus | 0.0000 | 0.0058 | 0.0010 |
| Heart | 0.0295 | 0.1045 | 0.0169 |
| Diaphragm | 0.0028 | 0.0221 | 0.0710 |
| Lung | 0.0011 | 0.0006 | 0.0000 |
| Spleen | 0.2548 | 0.1192 | 0.1910 |
| Inguinal LN | 0.0155 | 0.1676 | 0.0709 |
| Hepatic LN | 0.0047 | 0.0000 | 0.0096 |
| Liver L lateral | 0.4130 | 1.2144 | 3.0800 |
| Liver R lateral | 3.7770 | 0.3757 | 0.6073 |
| Liver L medial | 5.8697 | 0.2917 | 2.8207 |
| Liver R medial | 1.405 | 4.1749 | 0.8886 |
| Tissue . | No IS . | MMF, sirolimus, daclizumab . | MMF, sirolimus . |
|---|---|---|---|
| Kidney | 0.0109 | 0.0967 | 0.0562 |
| Cortex | 0.0197 | 0.0217 | 0.0254 |
| Testis | 0.0213 | 0.0843 | 0.0623 |
| Psoas | 0.0022 | 0.0014 | 0.0000 |
| Thymus | 0.0000 | 0.0058 | 0.0010 |
| Heart | 0.0295 | 0.1045 | 0.0169 |
| Diaphragm | 0.0028 | 0.0221 | 0.0710 |
| Lung | 0.0011 | 0.0006 | 0.0000 |
| Spleen | 0.2548 | 0.1192 | 0.1910 |
| Inguinal LN | 0.0155 | 0.1676 | 0.0709 |
| Hepatic LN | 0.0047 | 0.0000 | 0.0096 |
| Liver L lateral | 0.4130 | 1.2144 | 3.0800 |
| Liver R lateral | 3.7770 | 0.3757 | 0.6073 |
| Liver L medial | 5.8697 | 0.2917 | 2.8207 |
| Liver R medial | 1.405 | 4.1749 | 0.8886 |