Characteristics of disease during infection with P falciparum– and plasmodia-infecting mouse strains
| Parameter . | Human . | Mouse . | ||
|---|---|---|---|---|
| P bergeii/Balb/c* . | P chabaudi/A/J . | |||
| Parasitemia, % | 2.672 | 15.7106 | 0.957 | 50–60109 |
| Hematocrit level, % | 12.972 | NR | NR | 10–15109 |
| Hemoglobin concentration, g/dL | 472 | < 5106 | 55% of baseline57 | NR |
| Erythropoietin, mU/mL | 503372 | 1000106 | NR | 1000–3000109 |
| Parameter . | Human . | Mouse . | ||
|---|---|---|---|---|
| P bergeii/Balb/c* . | P chabaudi/A/J . | |||
| Parasitemia, % | 2.672 | 15.7106 | 0.957 | 50–60109 |
| Hematocrit level, % | 12.972 | NR | NR | 10–15109 |
| Hemoglobin concentration, g/dL | 472 | < 5106 | 55% of baseline57 | NR |
| Erythropoietin, mU/mL | 503372 | 1000106 | NR | 1000–3000109 |
Representative values for parameters measured in patients who present with SMA are given for comparison with values obtained from a sample of studies in mice. For a more detailed study on the changes in erythropoietin and severity of anemia during infection with P falciparum see Casals-Pascual.72
NR indicates not reported.
Hb levels reported in this study were given as a percent of baseline values determined in noninfected mice.