WHO histologic classification of lymphoid neoplasms
| Precursor B-cell and T-cell neoplasms |
| Precursor B-lymphoblastic leukemia/lymphoblastic lymphoma (precursor B-cell acute lymphoblastic leukemia) |
| Precursor T-lymphoblastic leukemia/lymphoblastic lymphoma (precursor T-cell acute lymphoblastic leukemia) |
| Mature B-cell neoplasms |
| Chronic lymphocytic leukemia/small lymphocytic lymphoma |
| B-cell prolymphocytic leukemia |
| Lymphoplasmacytic lymphoma |
| Splenic marginal zone lymphoma |
| Hairy-cell leukemia |
| Plasma-cell myleoma |
| MGUS |
| Solitary plasmactyoma of bone |
| Extraosseous plasmacytoma |
| Primary amyloidosis |
| Heavy-chain diseases |
| MALT lymphoma |
| Nodal marginal zone B-cell lymphoma |
| Follicular lymphoma |
| Mantle-cell lymphoma |
| Diffuse large B-cell lymphoma |
| Mediastinal (thymic) large B-cell lymphoma |
| Intravascular large B-cell lymphoma |
| Primary effusion lymphoma |
| Burkitt lymphoma/leukemia |
| Mature T-cell and NK-cell neoplasms |
| Leukemic/disseminated |
| T-cell prolymphocytic leukemia |
| T-cell large granular lymphocytic leukemia |
| Aggressive NK-cell leukemia |
| Adult T-cell leukemia/lymphoma |
| Cutaneous |
| Mycosis fungoides |
| Sezary syndrome |
| Primary cutaneous anaplastic large-cell lymphoma |
| Lymphomatoidpapulosis |
| Other extranodal |
| Extranodal NK/T-cell lymphoma, nasal type |
| Enteropathy-type T-cell lymphoma |
| Hepatosplenic T-cell lymphoma |
| Subcutaneous panniculitis–like T-cell lymphoma |
| Nodal |
| Angioimmunoblastic T-cell lymphoma |
| Peripheral T-cell lymphoma, unspecified |
| Anaplastic large-cell lymphoma |
| Neoplasm of uncertain lineage and stage of differentiation |
| Blastic NK-cell lymphoma |
| Precursor B-cell and T-cell neoplasms |
| Precursor B-lymphoblastic leukemia/lymphoblastic lymphoma (precursor B-cell acute lymphoblastic leukemia) |
| Precursor T-lymphoblastic leukemia/lymphoblastic lymphoma (precursor T-cell acute lymphoblastic leukemia) |
| Mature B-cell neoplasms |
| Chronic lymphocytic leukemia/small lymphocytic lymphoma |
| B-cell prolymphocytic leukemia |
| Lymphoplasmacytic lymphoma |
| Splenic marginal zone lymphoma |
| Hairy-cell leukemia |
| Plasma-cell myleoma |
| MGUS |
| Solitary plasmactyoma of bone |
| Extraosseous plasmacytoma |
| Primary amyloidosis |
| Heavy-chain diseases |
| MALT lymphoma |
| Nodal marginal zone B-cell lymphoma |
| Follicular lymphoma |
| Mantle-cell lymphoma |
| Diffuse large B-cell lymphoma |
| Mediastinal (thymic) large B-cell lymphoma |
| Intravascular large B-cell lymphoma |
| Primary effusion lymphoma |
| Burkitt lymphoma/leukemia |
| Mature T-cell and NK-cell neoplasms |
| Leukemic/disseminated |
| T-cell prolymphocytic leukemia |
| T-cell large granular lymphocytic leukemia |
| Aggressive NK-cell leukemia |
| Adult T-cell leukemia/lymphoma |
| Cutaneous |
| Mycosis fungoides |
| Sezary syndrome |
| Primary cutaneous anaplastic large-cell lymphoma |
| Lymphomatoidpapulosis |
| Other extranodal |
| Extranodal NK/T-cell lymphoma, nasal type |
| Enteropathy-type T-cell lymphoma |
| Hepatosplenic T-cell lymphoma |
| Subcutaneous panniculitis–like T-cell lymphoma |
| Nodal |
| Angioimmunoblastic T-cell lymphoma |
| Peripheral T-cell lymphoma, unspecified |
| Anaplastic large-cell lymphoma |
| Neoplasm of uncertain lineage and stage of differentiation |
| Blastic NK-cell lymphoma |
MGUS indicates monoclonal gammopathy of undetermined significance; MALT lymphoma, extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue; and NK, natural killer.
Adapted with permission from Jaffe et al.4