Semen quality, paternity, and number of offspring produced by 5 male CLAD dogs after nonmyeloablative conditioning for SCT
. | . | . | Semen analysis after SCT . | . | . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Dog . | Source of HSCs . | Time after SCT, y . | Sperm count, × 106 . | Motility, % . | Morphology, % normal . | Litters sired after SCT (no. puppies) . | |||
| M1* | BM | 1/4 | 1143/1348 | 70/90 | 87/92 | 2 (15) | |||
| M2 | BM | 2 | High concentration | Good | High percentage | 1 (5) | |||
| M3 | PBSCs | 3 | 543 | 75 | 92 | 1 (6) | |||
| M4 | BM | 3 | 585 | 90 | 93 | 2 (11) | |||
| M5 | CD34+ BM | 3 | High concentration | Good | High percentage | 3 (28) | |||
. | . | . | Semen analysis after SCT . | . | . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Dog . | Source of HSCs . | Time after SCT, y . | Sperm count, × 106 . | Motility, % . | Morphology, % normal . | Litters sired after SCT (no. puppies) . | |||
| M1* | BM | 1/4 | 1143/1348 | 70/90 | 87/92 | 2 (15) | |||
| M2 | BM | 2 | High concentration | Good | High percentage | 1 (5) | |||
| M3 | PBSCs | 3 | 543 | 75 | 92 | 1 (6) | |||
| M4 | BM | 3 | 585 | 90 | 93 | 2 (11) | |||
| M5 | CD34+ BM | 3 | High concentration | Good | High percentage | 3 (28) | |||
The conditioning regimen was 200 cGy TBI for each dog
HSCs indicates hematopoietic stem cells; M, male; BM, bone marrow; PBSCs, peripheral-blood stem cells; BM CD34+, CD34+ fraction of bone marrow
Two sets of data are provided for this dog because semen was evaluated at 2 time points after SCT