Table 1. Phenotype of KPM mice and... | American Society of Hematology

Table 1.

Phenotype of KPM+ mice and controls

Genotype	pl-pC	WBC × 10³ per μL (median)	Hct % (median)	Platelets per μL (median)	Spleen weight mg (median)	Liver weight mg (median)	Phenotype
KPM	+	61-512 (181) n = 9	14-45 (30) n = 9	81-1151 (501) n = 9	840-2308 (1324) n = 9	1220-2880 (2131) n = 9	APL^*
KPM	+	30-603 (211) n = 4	21-34 (28) n = 4	452-811 (563) n = 4	1170-1810 (1395) n = 4	2000-3240 (2482) n = 4	MPD
KM	+	15-111 (59) n = 18	9-44 (30) n = 18	515-1456 (891) n = 18	270-1690 (606) n = 19	790-2110 (1390) n = 19	MPD
KP	+	2.5-6.2 (4.4) n = 5	42-48 (45) n = 5	306-746 (598) n = 5	240-300 (268) n = 6	1050-1660 (1318) n = 6	Myeloid hyperplasia (APL†)

Genotype	pl-pC	WBC × 10³ per μL (median)	Hct % (median)	Platelets per μL (median)	Spleen weight mg (median)	Liver weight mg (median)	Phenotype
KPM	+	61-512 (181) n = 9	14-45 (30) n = 9	81-1151 (501) n = 9	840-2308 (1324) n = 9	1220-2880 (2131) n = 9	APL^*
KPM	+	30-603 (211) n = 4	21-34 (28) n = 4	452-811 (563) n = 4	1170-1810 (1395) n = 4	2000-3240 (2482) n = 4	MPD
KM	+	15-111 (59) n = 18	9-44 (30) n = 18	515-1456 (891) n = 18	270-1690 (606) n = 19	790-2110 (1390) n = 19	MPD
KP	+	2.5-6.2 (4.4) n = 5	42-48 (45) n = 5	306-746 (598) n = 5	240-300 (268) n = 6	1050-1660 (1318) n = 6	Myeloid hyperplasia (APL†)

Normal mouse spleen weight was 70 to 130 mg. Normal mouse WBC count was 3 to 9 × 10³ per μL

High penetrance disease with short latency

Low penetrance disease with long latency