European consensus on grading bone marrow fibrosis (fiber density should be assessed in hematopoietic cellular areas)
Fibrosis grade . | Description . |
|---|---|
| 0 | Scattered linear reticulin with no intersections corresponding to normal bone marrow |
| 1 | Loose network of reticulin with many intersections, especially in perivascular areas |
| 2 | Diffuse and dense increase in reticulin with extensive intersections, occasionally with only focal bundles of collagen and/or focal osteosclerosis |
| 3 | Diffuse and dense increase in reticulin with extensive intersections with coarse bundles of collagen, often associated with significant osteosclerosis |
Fibrosis grade . | Description . |
|---|---|
| 0 | Scattered linear reticulin with no intersections corresponding to normal bone marrow |
| 1 | Loose network of reticulin with many intersections, especially in perivascular areas |
| 2 | Diffuse and dense increase in reticulin with extensive intersections, occasionally with only focal bundles of collagen and/or focal osteosclerosis |
| 3 | Diffuse and dense increase in reticulin with extensive intersections with coarse bundles of collagen, often associated with significant osteosclerosis |