Table 1. Baseline characteristics of... | American Society of Hematology

Table 1.

Baseline characteristics of patients

Parameter	No. patients (%)
Age 75 y or older	40 (22.1)
Men/women	111/70 (61.3/38.7)
Weight, kg, median [range]	75 [39-130]
History of heparin treatment within the previous 3 mo^*	47 (26.0)
Unfractionated heparin	25 (13.8)
Low-molecular-weight heparin	21 (11.6)
Medical morbidity
History of venous thrombosis^*	21 (11.6)
History of arterial thrombosis^*	15 (8.3)
Cancer	30 (16.6)
High blood pressure	78 (43.1)
Ischemic coronary disease	51 (28.2)
Cardiac rhythm disorder	32 (17.7)
History of stroke	10 (5.5)
Chronic respiratory insufficiency	23 (12.7)
Diabetes	42 (23.2)
Creatinine clearance below 60 mL/min†	59 (44.7)‡

Parameter	No. patients (%)
Age 75 y or older	40 (22.1)
Men/women	111/70 (61.3/38.7)
Weight, kg, median [range]	75 [39-130]
History of heparin treatment within the previous 3 mo^*	47 (26.0)
Unfractionated heparin	25 (13.8)
Low-molecular-weight heparin	21 (11.6)
Medical morbidity
History of venous thrombosis^*	21 (11.6)
History of arterial thrombosis^*	15 (8.3)
Cancer	30 (16.6)
High blood pressure	78 (43.1)
Ischemic coronary disease	51 (28.2)
Cardiac rhythm disorder	32 (17.7)
History of stroke	10 (5.5)
Chronic respiratory insufficiency	23 (12.7)
Diabetes	42 (23.2)
Creatinine clearance below 60 mL/min†	59 (44.7)‡

N = 181 patients. The median age was 67 years (range, 17-95 years); median creatinine clearance was 62 mL/min (range, 9-171 mL/min)

Before the current episode of HIT

Immediately before the administration of lepirudin

n = 132