Table 4.

Causes of death



No. patients

HLA-identical
HLA-nonidentical
Diffuse alveolar damage   4   2  
Systemic viral infections   0   3  
Systemic fungal infections   2   0  
Multiorgan failure   4   4  
TTP   2   0  
Acute GVHD and associated problems   4   2 
Chronic GVHD   5   1  
Complications from second transplantation   1   1  
Miscellaneous*  2   2  
Total (%)
 
24 (39)
 
15 (60)
 


No. patients

HLA-identical
HLA-nonidentical
Diffuse alveolar damage   4   2  
Systemic viral infections   0   3  
Systemic fungal infections   2   0  
Multiorgan failure   4   4  
TTP   2   0  
Acute GVHD and associated problems   4   2 
Chronic GVHD   5   1  
Complications from second transplantation   1   1  
Miscellaneous*  2   2  
Total (%)
 
24 (39)
 
15 (60)
 

CNS indicates central nervous system; GVHD, graft-versus-host disease; TTP, thrombotic, thrombocytopenic purpura

*

One each from asphyxia as a result of aspiration, CNS hemorrhage, secondary graft failure, and suicide

Both patients developed posttransplantation lymphoproliferative disorders following extensive treatment for acute GVHD

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