Causes of death
. | No. patients . | . | |
---|---|---|---|
. | HLA-identical . | HLA-nonidentical . | |
Diffuse alveolar damage | 4 | 2 | |
Systemic viral infections | 0 | 3 | |
Systemic fungal infections | 2 | 0 | |
Multiorgan failure | 4 | 4 | |
TTP | 2 | 0 | |
Acute GVHD and associated problems | 4 | 2† | |
Chronic GVHD | 5 | 1 | |
Complications from second transplantation | 1 | 1 | |
Miscellaneous* | 2 | 2 | |
Total (%) | 24 (39) | 15 (60) |
. | No. patients . | . | |
---|---|---|---|
. | HLA-identical . | HLA-nonidentical . | |
Diffuse alveolar damage | 4 | 2 | |
Systemic viral infections | 0 | 3 | |
Systemic fungal infections | 2 | 0 | |
Multiorgan failure | 4 | 4 | |
TTP | 2 | 0 | |
Acute GVHD and associated problems | 4 | 2† | |
Chronic GVHD | 5 | 1 | |
Complications from second transplantation | 1 | 1 | |
Miscellaneous* | 2 | 2 | |
Total (%) | 24 (39) | 15 (60) |
CNS indicates central nervous system; GVHD, graft-versus-host disease; TTP, thrombotic, thrombocytopenic purpura
One each from asphyxia as a result of aspiration, CNS hemorrhage, secondary graft failure, and suicide
Both patients developed posttransplantation lymphoproliferative disorders following extensive treatment for acute GVHD