Patient outcomes
Patient group . | No. . | Site of first relapse . | Deaths . | Survivors in CR, mo after diagnosis . |
|---|---|---|---|---|
| Failure to attain CR1 | 8 | — | — | — |
| Induction (toxic) death | 4 | — | At 4 d, 25 d, 32 d, 36 d | — |
| Died due to resistant disease | 3 | — | At 78 d, 207 d, 504 d | — |
| MRD without remission | 1 | 1 CNS | 1 after relapse | — |
| Attained CR1 | 69 | — | — | — |
| MUD allograft, CR1 | 5 | 1 BM | 2 in CR1, 1 after relapse | 71, 42 |
| MRD allograft, CR1 | 25 | 1 CNS, 1 BM, 1 BM + CNS, 1 BM + ocular, 1 arm mass | 9 in CR1, 5 after relapse | 29, 34, 38, 49, 52, 57, 65, 67, 71, 75, 102 |
| Autograft, CR1 | 6 | 3 BM, 1 BM + CNS | 1 in CR1, 4 after relapse | 35 |
| Chemotherapy, CR1 | 27 | 11 BM, 1 BM + CNS, 1 testes, 1 skin | 6 in CR1, 14 after relapse | 56, 59, 59, 91, 102, 130, 137 |
| MRD allograft beyond CR1 | 3 | 3 BM | 2 after 2nd relapse | 58 |
| MUD allograft beyond CR1 | 3 | 1 CNS, 2 BM | 2 after 2nd relapse | 46 |
| Total | 77 | — | — | — |
Patient group . | No. . | Site of first relapse . | Deaths . | Survivors in CR, mo after diagnosis . |
|---|---|---|---|---|
| Failure to attain CR1 | 8 | — | — | — |
| Induction (toxic) death | 4 | — | At 4 d, 25 d, 32 d, 36 d | — |
| Died due to resistant disease | 3 | — | At 78 d, 207 d, 504 d | — |
| MRD without remission | 1 | 1 CNS | 1 after relapse | — |
| Attained CR1 | 69 | — | — | — |
| MUD allograft, CR1 | 5 | 1 BM | 2 in CR1, 1 after relapse | 71, 42 |
| MRD allograft, CR1 | 25 | 1 CNS, 1 BM, 1 BM + CNS, 1 BM + ocular, 1 arm mass | 9 in CR1, 5 after relapse | 29, 34, 38, 49, 52, 57, 65, 67, 71, 75, 102 |
| Autograft, CR1 | 6 | 3 BM, 1 BM + CNS | 1 in CR1, 4 after relapse | 35 |
| Chemotherapy, CR1 | 27 | 11 BM, 1 BM + CNS, 1 testes, 1 skin | 6 in CR1, 14 after relapse | 56, 59, 59, 91, 102, 130, 137 |
| MRD allograft beyond CR1 | 3 | 3 BM | 2 after 2nd relapse | 58 |
| MUD allograft beyond CR1 | 3 | 1 CNS, 2 BM | 2 after 2nd relapse | 46 |
| Total | 77 | — | — | — |
CR1 indicates first complete remission; MUD, matched unrelated donor; MRD, matched related donor; —, not applicable.