Table 4.

Frequency (percent) of deaths and causes of death among all HIV-positive individuals with hemophilia in Canada (1982-2003) by age at time of HIV seroconversion (in 1982)



Age at seroconversion


Under 16 y
16-24 y
25-34 y
More than 34 y
All
P
No.   238   192   135   95   660   
Alive, no. (%)   131 (55.0)   81 (42.2)   34 (25.2)   8 (8.4)   254 (38.5)   < .001* 
Dead, no. (%)   107 (45.0)   111 (57.8)   101 (74.8)   87 (91.6)   406 (61.5)   
Primary cause of death, no. (% of all deaths)       .038 
    AIDS   80 (74.8)   79 (71.2)   64 (63.4)   60 (69.0)   283 (69.7)   
    Liver disease   8 (7.5)   10 (9.0)   17 (16.8)   12 (13.8)   47 (11.6)   
    Bleeding   4 (3.7)   6 (5.4)   6 (5.9)   2 (2.3)   18 (4.4)   
    Infection   4 (3.7)   1 (0.9)   7 (7.0)   5 (5.8)   17 (4.2)   
    Unknown   4 (3.7)   5 (4.5)   2 (2.0)   0 (0.0)   11 (2.7)   
    Suicide   5 (4.7)   4 (3.6)   1 (1.0)   0 (0.0)   10 (2.5)   
    Accidental   1 (0.9)   5 (4.5)   1 (1.0)   3 (3.5)   10 (2.5)   
    Cancer   0 (0.0)   0 (0.0)   1 (1.0)   3 (3.5)   4 (1.0)   
    Cardiovascular   0 (0.0)   1 (0.9)   1 (1.0)   1 (1.2)   3 (0.7)   
    Other
 
1 (0.9)
 
0 (0.0)
 
1 (1.0)
 
1 (1.2)
 
3 (0.7)
 

 


Age at seroconversion


Under 16 y
16-24 y
25-34 y
More than 34 y
All
P
No.   238   192   135   95   660   
Alive, no. (%)   131 (55.0)   81 (42.2)   34 (25.2)   8 (8.4)   254 (38.5)   < .001* 
Dead, no. (%)   107 (45.0)   111 (57.8)   101 (74.8)   87 (91.6)   406 (61.5)   
Primary cause of death, no. (% of all deaths)       .038 
    AIDS   80 (74.8)   79 (71.2)   64 (63.4)   60 (69.0)   283 (69.7)   
    Liver disease   8 (7.5)   10 (9.0)   17 (16.8)   12 (13.8)   47 (11.6)   
    Bleeding   4 (3.7)   6 (5.4)   6 (5.9)   2 (2.3)   18 (4.4)   
    Infection   4 (3.7)   1 (0.9)   7 (7.0)   5 (5.8)   17 (4.2)   
    Unknown   4 (3.7)   5 (4.5)   2 (2.0)   0 (0.0)   11 (2.7)   
    Suicide   5 (4.7)   4 (3.6)   1 (1.0)   0 (0.0)   10 (2.5)   
    Accidental   1 (0.9)   5 (4.5)   1 (1.0)   3 (3.5)   10 (2.5)   
    Cancer   0 (0.0)   0 (0.0)   1 (1.0)   3 (3.5)   4 (1.0)   
    Cardiovascular   0 (0.0)   1 (0.9)   1 (1.0)   1 (1.2)   3 (0.7)   
    Other
 
1 (0.9)
 
0 (0.0)
 
1 (1.0)
 
1 (1.2)
 
3 (0.7)
 

 
*

Exact 2-sided test for trend over age groups of the proportion who died.

Exact 2-sided test of association.

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