Comparison of primary causes of death among HIV-positive and HIV-negative individuals with hemophilia in Canada (1982-2003)
Cause of death . | HIV-positive, no. (%) . | HIV-negative, no. (%) . |
|---|---|---|
| AIDS | 283 (69.7) | 2 (1.8)* |
| Liver disease† | 47 (11.6) | 13 (11.4) |
| Bleeding‡ | 18 (4.4) | 25 (21.9) |
| Infection | 17 (4.2) | 4 (3.5) |
| Unknown | 11 (2.7) | 13 (11.4) |
| Suicide | 10 (2.5) | 4 (3.5) |
| Accidental | 10 (2.5) | 10 (8.8) |
| Cancer | 4 (1.0) | 14 (12.3) |
| Cardiovascular | 3 (0.7) | 20 (17.5) |
| Other | 3 (0.7) | 9 (7.9) |
| All causes | 406 (100) | 114 (100) |
Cause of death . | HIV-positive, no. (%) . | HIV-negative, no. (%) . |
|---|---|---|
| AIDS | 283 (69.7) | 2 (1.8)* |
| Liver disease† | 47 (11.6) | 13 (11.4) |
| Bleeding‡ | 18 (4.4) | 25 (21.9) |
| Infection | 17 (4.2) | 4 (3.5) |
| Unknown | 11 (2.7) | 13 (11.4) |
| Suicide | 10 (2.5) | 4 (3.5) |
| Accidental | 10 (2.5) | 10 (8.8) |
| Cancer | 4 (1.0) | 14 (12.3) |
| Cardiovascular | 3 (0.7) | 20 (17.5) |
| Other | 3 (0.7) | 9 (7.9) |
| All causes | 406 (100) | 114 (100) |
There were 660 HIV-positive and 1767 HIV-negative individuals, exact 2-sided test of association, P < .001.
Two patients died with AIDS-defining illness before the availability of HIV testing.
Four patients in the HIV-positive group, and 3 in the HIV-negative group had hepatoma.
Ten bleeding deaths were in patients with inhibitors.