Table 2.

Frequency (percent) of primary causes of death among all HIV-positive individuals with hemophilia in Canada by year of death before (1982-1997) and after (1998-2003) the adoption of highly active antiretroviral therapy



Year of death, no. (%)*
Cause of death*
1982-1997
1998-2003
All
AIDS   256 (74.6)   27 (42.9)   283 (69.7)  
Liver disease   30 (8.7)   17 (27.0)   47 (11.6)  
Bleeding   12 (3.5)   6 (9.5)   18 (4.4)  
Infection   14 (4.1)   3 (4.8)   17 (4.2)  
Unknown   5 (1.5)   6 (9.5)   11 (2.7)  
Suicide   7 (2.0)   3 (4.8)   10 (2.5)  
Accidental   10 (2.9)   0 (0.0)   10 (2.5)  
Cancer   4 (1.2)   0 (0.0)   4 (1.0)  
Cardiovascular   2 (0.6)   1 (1.6)   3 (0.7)  
Other   3 (0.9)   0 (0.0)   3 (0.7)  
All causes
 
343 (100)
 
63 (100)
 
406 (100)
 


Year of death, no. (%)*
Cause of death*
1982-1997
1998-2003
All
AIDS   256 (74.6)   27 (42.9)   283 (69.7)  
Liver disease   30 (8.7)   17 (27.0)   47 (11.6)  
Bleeding   12 (3.5)   6 (9.5)   18 (4.4)  
Infection   14 (4.1)   3 (4.8)   17 (4.2)  
Unknown   5 (1.5)   6 (9.5)   11 (2.7)  
Suicide   7 (2.0)   3 (4.8)   10 (2.5)  
Accidental   10 (2.9)   0 (0.0)   10 (2.5)  
Cancer   4 (1.2)   0 (0.0)   4 (1.0)  
Cardiovascular   2 (0.6)   1 (1.6)   3 (0.7)  
Other   3 (0.9)   0 (0.0)   3 (0.7)  
All causes
 
343 (100)
 
63 (100)
 
406 (100)
 
*

Exact 2-sided test of association, P < .001.

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