Association of FCGR2B haplotypes with FcγRIIa/FcγRIIb2 mRNA ratios in neutrophils
. | FcγRIIa/FcγRIIb2 mRNA ratio . | . | |
|---|---|---|---|
. | 1:1 . | 2:1 or higher . | |
| Genotype, no. subjects (% of group) | |||
| 2B.1/2B.1 | 6 (35) | 25 (96) | |
| 2B.1/2B.4 | 10 (59) | 1 (4) | |
| 2B.4/2B.4 | 0 (0) | 0 (0) | |
| Haplotype frequency, % | |||
| 2B.1 (-386G/-120T) | 68.8 | 98.0 | |
| 2B.4 (-386C/-120A) | 31.2 | 2.0 | |
. | FcγRIIa/FcγRIIb2 mRNA ratio . | . | |
|---|---|---|---|
. | 1:1 . | 2:1 or higher . | |
| Genotype, no. subjects (% of group) | |||
| 2B.1/2B.1 | 6 (35) | 25 (96) | |
| 2B.1/2B.4 | 10 (59) | 1 (4) | |
| 2B.4/2B.4 | 0 (0) | 0 (0) | |
| Haplotype frequency, % | |||
| 2B.1 (-386G/-120T) | 68.8 | 98.0 | |
| 2B.4 (-386C/-120A) | 31.2 | 2.0 | |
n = 44; Fisher exact test, OR 0.05; P < .001.