Table 3.

Univariate and multivariate analysis: overall survival and disease-free survival



OS

DFS
Univariate
Multivariate
Univariate
Multivariate

HR (95% CI)
P
HR (95% CI)
P
HR (95% CI)
P
HR (95% CI)
P
CECs at 2 mo         
    More than 11/μL   1.00    1.00    1.00    1.00   
    0-11/μL   2.76 (1.26-6.04)   .01*   2.30 (1.02-5.19)   .04*   1.93 (1.20-3.13)   .007*   1.96 (1.19-3.24)   .009*  
No. of metastatic sites         
    1-2   1.00    1.00    1.00    1.00   
    3+   2.65 (1.16-6.06)   .02*   1.79 (0.76-4.23)   .18   1.33 (0.60-2.91)   .48   0.90 (0.39-2.06)   .80  
Liver metastasis         
    No   1.00    1.00    1.00    1.00   
    Yes
 
1.89 (0.99-3.60)
 
.05
 
1.60 (0.83-3.07)
 
.16
 
1.12 (0.69-1.83)
 
.65
 
1.08 (0.66-1.77)
 
.77
 


OS

DFS
Univariate
Multivariate
Univariate
Multivariate

HR (95% CI)
P
HR (95% CI)
P
HR (95% CI)
P
HR (95% CI)
P
CECs at 2 mo         
    More than 11/μL   1.00    1.00    1.00    1.00   
    0-11/μL   2.76 (1.26-6.04)   .01*   2.30 (1.02-5.19)   .04*   1.93 (1.20-3.13)   .007*   1.96 (1.19-3.24)   .009*  
No. of metastatic sites         
    1-2   1.00    1.00    1.00    1.00   
    3+   2.65 (1.16-6.06)   .02*   1.79 (0.76-4.23)   .18   1.33 (0.60-2.91)   .48   0.90 (0.39-2.06)   .80  
Liver metastasis         
    No   1.00    1.00    1.00    1.00   
    Yes
 
1.89 (0.99-3.60)
 
.05
 
1.60 (0.83-3.07)
 
.16
 
1.12 (0.69-1.83)
 
.65
 
1.08 (0.66-1.77)
 
.77
 

HR indicates hazard ratio.

All the results in the table (HR and P) are obtained from a Cox proportional hazard regression model. The first 2 colums are from a univariate model; the next 2 columns are from a multivariate model.

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